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5k0t

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==Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415==
==Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415==
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<StructureSection load='5k0t' size='340' side='right' caption='[[5k0t]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='5k0t' size='340' side='right'caption='[[5k0t]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5k0t]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ppw 4ppw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K0T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5k0t]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Brusu Brusu]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ppw 4ppw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K0T OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5K0T FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=415:1-{3-[(3-CHLORO-5-METHOXYBENZYL)AMINO]PROPYL}-3-PHENYLUREA'>415</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=415:1-{3-[(3-CHLORO-5-METHOXYBENZYL)AMINO]PROPYL}-3-PHENYLUREA'>415</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k0s|5k0s]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k0s|5k0s]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">metG, BR0995, BS1330_I0991 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=204722 BRUSU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k0t OCA], [http://pdbe.org/5k0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k0t RCSB], [http://www.ebi.ac.uk/pdbsum/5k0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k0t ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5k0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k0t OCA], [http://pdbe.org/5k0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k0t RCSB], [http://www.ebi.ac.uk/pdbsum/5k0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k0t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5k0t" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5k0t" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brusu]]
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[[Category: Large Structures]]
[[Category: Methionine--tRNA ligase]]
[[Category: Methionine--tRNA ligase]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

Revision as of 09:13, 25 June 2020

Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415

PDB ID 5k0t

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