NudT16

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
==Structure==
==Structure==
-
<Structure load='6B09' size='350' frame='true' align='right' caption='Crystal structure of HsNUDT16 in complex with diADPR (soaked)' scene='Crystal' />
 
[[Image:Nudt16cartoon.png|300px|right|thumb| NudT16]]
[[Image:Nudt16cartoon.png|300px|right|thumb| NudT16]]
NudT16 is a dimer
NudT16 is a dimer
-
 
+
<Structure load='6B09' size='350' frame='true' align='right' caption='Crystal structure of HsNUDT16 in complex with diADPR (soaked)' scene='Crystal' />
== Function ==
== Function ==

Revision as of 15:40, 30 June 2020

Contents

Introduction

NudT16 is a hydrolase and belongs to the nucleoside diphosphate-linked moiety X (Nudix) family. This protein regulates levels of 53BP1 which is a protein that recruits other proteins to the site of a DNA breakage. NudT16 has also shown in vitro to remove ADP-ribosylation through its hydrolase activities.

Structure

NudT16
NudT16

NudT16 is a dimer

Crystal structure of HsNUDT16 in complex with diADPR (soaked)

Drag the structure with the mouse to rotate

Function

Disease

Relevance

Structural highlights

</StructureSection>

References

Proteopedia Page Contributors and Editors (what is this?)

Hannah Campbell, Tihitina Y Aytenfisu, Michal Harel, Sandra B. Gabelli

Personal tools