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2woa
From Proteopedia
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==MMP12 complex with a beta hydroxy carboxylic acid== | ==MMP12 complex with a beta hydroxy carboxylic acid== | ||
| - | <StructureSection load='2woa' size='340' side='right' caption='[[2woa]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='2woa' size='340' side='right'caption='[[2woa]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2woa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOA OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[2woa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WOA FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=576:(3S)-5-(9H-FLUOREN-2-YL)-3-HYDROXYPENTANOIC+ACID'>576</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=576:(3S)-5-(9H-FLUOREN-2-YL)-3-HYDROXYPENTANOIC+ACID'>576</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[1os9|1os9]], [[1utt|1utt]], [[1z3j|1z3j]], [[1y93|1y93]], [[2wo8|2wo8]], [[2w0d|2w0d]], [[1os2|1os2]], [[2wo9|2wo9]], [[1ros|1ros]], [[1jk3|1jk3]], [[1utz|1utz]], [[1jiz|1jiz]], [[1rmz|1rmz]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[1os9|1os9]], [[1utt|1utt]], [[1z3j|1z3j]], [[1y93|1y93]], [[2wo8|2wo8]], [[2w0d|2w0d]], [[1os2|1os2]], [[2wo9|2wo9]], [[1ros|1ros]], [[1jk3|1jk3]], [[1utz|1utz]], [[1jiz|1jiz]], [[1rmz|1rmz]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2woa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2woa OCA], [http://pdbe.org/2woa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2woa RCSB], [http://www.ebi.ac.uk/pdbsum/2woa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2woa ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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==See Also== | ==See Also== | ||
| - | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | + | *[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
[[Category: Amour, A J]] | [[Category: Amour, A J]] | ||
Revision as of 08:59, 1 July 2020
MMP12 complex with a beta hydroxy carboxylic acid
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Categories: Human | Large Structures | Macrophage elastase | Amour, A J | Baddeley, S J | Brown, D | Convery, M A | Egan, D | Gaines, S | Gross, J W | Herbert, S | Holmes, I P | Lorthioir, O | Martin, S L | Singh, O M.P | Smith, R H | Strelow, J M | Walker, A | Watson, S P | Calcium | Disulfide bond | Extracellular matrix | Glycoprotein | Hydrolase | Matrix metalloprotease mmp-12 complex structure | Metal-binding | Metalloprotease | Polymorphism | Protease | Secreted | Zinc | Zymogen

