Cell death protein

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[[Cell death protein 3D structures]]
[[Cell death protein 3D structures]]
</StructureSection>
</StructureSection>
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==3D structures of cell death protein==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*CED-1
 
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**[[3rrq]], [[6umu]], [[6umv]] - hCED-1 extracellular domain (mutant) - human<br />
 
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**[[2m2d]] - hCED-1 extracellular domain - NMR<br />
 
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**[[5wt9]], [[5jxe]], [[5b8c]] - hCED-1 extracellular domain + antibody<br />
 
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**[[5ggs]], [[5ggr]], [[6hig]], [[6j14]], [[6j15]], [[6jbt]], [[6jjp]], [[6k0y]], [[7bxa]] - hCED-1 extracellular domain (mutant) + antibody<br />
 
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**[[4zqk]], [[5ius]] - hCED-1 extracellular domain (mutant) + hCED-L1<br />
 
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**[[6umt]] - hCED-1 extracellular domain (mutant) + hCED-L2 extracellular domain<br />
 
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**[[1npu]] – mCED-1 extracellular domain (mutant) - mouse<br />
 
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**[[3bik]] - mCED-1 extracellular domain (mutant) + hCED-L1 extracellular domain<br />
 
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**[[3sbw]] - mCED-1 extracellular domain + hCED-L1 extracellular domain<br />
 
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**[[3rnq]] - mCED-1 extracellular domain + mCED-L2 extracellular domain<br />
 
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**[[3bp5]], [[3bp6]] - mCED-1 extracellular domain (mutant) + mCED-L2 extracellular domain<br />
 
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**[[3rnk]] - mCED-1 extracellular domain (mutant) + mCED-L2 IgV domain<br />
 
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*CED-2
 
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**[[3qwx]], [[3qwy]] - CeCED-2 – ''Caenorhabditis elegans''
 
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*CED-3
 
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**[[4m9r]] - nCED-3 - nematode<br />
 
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*CED-4
 
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**[[2ggf]] – hCED-4 MA3 domain – NMR<BR />
 
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**[[2rg8]], [[2kzt]] - hCED-4 MA3 domain<BR />
 
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**[[3eij]] - hCED-4 residues 157-469<BR />
 
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**[[2zu6]], [[3eiq]] - hCED-4 residues 163-469 + eukaryotic initiation factor 4A-I<br />
 
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**[[2iol]], [[2ion]], [[2ios]], [[2nsz]] - mCED-4 MA3 domain<BR />
 
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**[[2hm8]] - mCED-4 MA3 domain – NMR<BR />
 
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**[[4m9s]], [[4m9x]], [[4m9y]], [[4m9z]] - nCED-4 + nCED-3 fragment<br />
 
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**[[2a5y]] - CeCED-4 + CeCED-9 <BR />
 
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**[[3lqq]], [[3lqr]] - CeCED-4<BR />
 
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*CED-5
 
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**[[1yyb]] - hCED-5 N terminal – NMR<BR />
 
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**[[2cru]], [[2k6b]] - hCED-5 – NMR<BR />
 
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*CED-6
 
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**[[2zn8]], [[2zn9]], [[2znd]], [[2zrs]], [[2zrt]] - hCED-6<br />
 
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**[[3aaj]], [[3aak]] - hCED-6 (mutant)<br />
 
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**[[2zne]] - hCED-6 + CED-6-interacting protein<br />
 
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**[[3wxa]] - hCED-6 + SEC31A peptide<br />
 
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**[[5gqq]] - hCED-6 + heme-binding protein<br />
 
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**[[1hqv]] - mCED-6<br />
 
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**[[1y1x]] - CED-6 – ''Leishmania major''<br />
 
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*CED-8 (apoptosis-inducing factor 1)
 
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**[[1m6i]], [[4bv6]], [[4lii]] - hCED-8<br />
 
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**[[5fmh]], [[5kvh]], [[5kvi]], [[5fs6]], [[5fs7]], [[5fs8]], [[4fdc]] – hCED-8 (mutant) <br />
 
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**[[5fs9]] – hCED-8 (mutant) + FAD<br />
 
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**[[4bur]] – hCED-8 + NAD <br />
 
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**[[1gv4]], [[3gd3]] - mCED-8<br />
 
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**[[3gd4]] – mCED-8 + NAD <br />
 
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**[[5miu]] – mCED-8 (mutant) + FAD <br />
 
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**[[5miv]] – mCED-8 (mutant) + FAD + NAD<br />
 
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*CED-9
 
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**[[1ohu]] – CeCED-9 <BR />
 
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**[[1ty4]] - CeCED-9 + programmed CED activator
 
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*CED-10
 
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**[[3ajm]] - hCED-10 + inositol tetrakisphosphate<br />
 
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**[[3l8i]], [[3l8j]] - hCED-10<br />
 
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**[[3rqe]], [[3rqf]], [[3rqg]] - hCED-10 + paxillidin peptide<br />
 
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**[[3w8h]], [[3w8i]], [[4geh]] - hCED-10 + serine/threonine kinase regulatory domain<br />
 
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*CED-HAC-1
 
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**[[4v4l]] – CED-HAC-1 – ''Drosophila melanogaster''
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:14, 2 July 2020

Human CED-1 extracellular domain. Programmed cell death protein 1 (green and magenta) and programmed cell death 1 ligand 1 (cyan) complex with glycerol (PDB code 3bik)

Drag the structure with the mouse to rotate

References

  1. Zak KM, Kitel R, Przetocka S, Golik P, Guzik K, Musielak B, Domling A, Dubin G, Holak TA. Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1. Structure. 2015 Oct 22. pii: S0969-2126(15)00402-5. doi:, 10.1016/j.str.2015.09.010. PMID:26602187 doi:http://dx.doi.org/10.1016/j.str.2015.09.010
  2. Lin DY, Tanaka Y, Iwasaki M, Gittis AG, Su HP, Mikami B, Okazaki T, Honjo T, Minato N, Garboczi DN. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3011-6. Epub 2008 Feb 14. PMID:18287011

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