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2xke

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==Structure of Nek2 bound to Aminipyrazine Compound 5==
==Structure of Nek2 bound to Aminipyrazine Compound 5==
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<StructureSection load='2xke' size='340' side='right' caption='[[2xke]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='2xke' size='340' side='right'caption='[[2xke]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xke]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XKE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XKE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xke]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XKE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XKE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=WI2:1-[3-AMINO-6-(3-METHOXYPHENYL)PYRAZIN-2-YL]PIPERIDINE-4-CARBOXYLIC+ACID'>WI2</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=WI2:1-[3-AMINO-6-(3-METHOXYPHENYL)PYRAZIN-2-YL]PIPERIDINE-4-CARBOXYLIC+ACID'>WI2</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w5b|2w5b]], [[2w5a|2w5a]], [[2wqo|2wqo]], [[2jav|2jav]], [[2w5h|2w5h]], [[2xk4|2xk4]], [[2xkc|2xkc]], [[2xk8|2xk8]], [[2xk3|2xk3]], [[2xkd|2xkd]], [[2xk7|2xk7]], [[2xk6|2xk6]], [[2xkf|2xkf]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w5b|2w5b]], [[2w5a|2w5a]], [[2wqo|2wqo]], [[2jav|2jav]], [[2w5h|2w5h]], [[2xk4|2xk4]], [[2xkc|2xkc]], [[2xk8|2xk8]], [[2xk3|2xk3]], [[2xkd|2xkd]], [[2xk7|2xk7]], [[2xk6|2xk6]], [[2xkf|2xkf]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xke OCA], [http://pdbe.org/2xke PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xke RCSB], [http://www.ebi.ac.uk/pdbsum/2xke PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xke ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xke OCA], [http://pdbe.org/2xke PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xke RCSB], [http://www.ebi.ac.uk/pdbsum/2xke PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xke ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
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*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Bayliss, R]]
[[Category: Bayliss, R]]

Revision as of 15:17, 8 July 2020

Structure of Nek2 bound to Aminipyrazine Compound 5

PDB ID 2xke

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