User:Eric Martz/MHC Quiz
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(Difference between revisions)
(New page: ==Antibody Quiz== You will get immediate feedback when you click ''Submit'' (at the bottom of the quiz). The quiz below is offered to accompany the Antibody structure tutorial at [http://...) |
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==Antibody Quiz== | ==Antibody Quiz== | ||
| - | You will get immediate feedback when you click ''Submit'' (at the bottom of the quiz). | + | You will get immediate feedback when you click ''Submit'' (at the bottom of the quiz). This quiz is offered to accompany the MHC structure tutorial at [http://molviz.org MolviZ.Org]. |
<!-- (i) = case Insensitive. _7 = width of slot (number of characters) for answer. --> | <!-- (i) = case Insensitive. _7 = width of slot (number of characters) for answer. --> | ||
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| - | { | ||
| - | |type="{}"} | ||
| - | How many '''Fab''' "arms" does one antibody molecule have? | ||
| - | { 2|two (i)|two. (i) _7 } | ||
| - | || | ||
| - | { | ||
| - | |type="{}"} | ||
| - | How many '''Fc''' "arms" does one antibody molecule have? | ||
| - | { 1|one (i)|one. (i) _7 } | ||
| - | || | ||
| - | |||
| - | { | ||
| - | |type="{}"} | ||
| - | How many CDRs are in one paratope? | ||
| - | { 6|six (i)|six. (i) _7 } | ||
| - | ||Three in the light chain variable domain plus three in the heavy chain variable domain. | ||
| - | |||
| - | { | ||
| - | |type="{}"} | ||
| - | What is the term for the smallest part of IgG1 that binds to antigen? | ||
| - | { Fv (i)|Fv. (i) _7 } | ||
| - | ||The variable fragment, containing only the variable domains: Fv. | ||
{<hr>'''An IgG1 molecule has a molecular weight of 150 kilo Daltons.'''} | {<hr>'''An IgG1 molecule has a molecular weight of 150 kilo Daltons.'''} | ||
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{ 10-13 _7 } kD. | { 10-13 _7 } kD. | ||
||Twelve Ig domains in one IgG1 molecule. 150/12 = 12.5 kD. | ||Twelve Ig domains in one IgG1 molecule. 150/12 = 12.5 kD. | ||
| - | |||
| - | { | ||
| - | |type="{}"} | ||
| - | What is the approximate molecular weight of a single Fc in kD? | ||
| - | { 48-55 _7 } kD. | ||
| - | ||Fc is one of three roughly equal-sized arms, each containing 8 Ig domains. 150/3 = 50 kD. | ||
{<hr> | {<hr> | ||
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| - | {Antibody molecules consist of | ||
| - | |type="[]"} | ||
| - | + Protein. | ||
| - | - Lipid. | ||
| - | - Salt. | ||
| - | + Sugars. | ||
| - | + Carbohydrate. | ||
| - | + Amino acids. | ||
| - | - Fatty acids. | ||
| - | + Immunoglobulin domains. | ||
| - | || | ||
| - | {Antibody is manufactured by | ||
| - | |type="[]"} | ||
| - | - T lymphocytes. | ||
| - | - The liver. | ||
| - | + B lymphocytes. | ||
| - | - Antigen. | ||
| - | - G lymphocytes. | ||
| - | - Macrophages. | ||
| - | || | ||
| - | |||
| - | {Variable immunoglobulin domains | ||
| - | |type="[]"} | ||
| - | + Are in Fab. | ||
| - | - Are in Fc. | ||
| - | + Are in all antibodies. | ||
| - | - Have no disulfide bonds. | ||
| - | - Do not contain CDRs. | ||
| - | - Make up the epitope. | ||
| - | + Make up the paratope. | ||
| - | - Have the same amino acid sequence in all antibodies of a given subclass. | ||
| - | || | ||
| - | |||
| - | {A single immunoglobulin domain contains | ||
| - | |type="[]"} | ||
| - | - Three beta sheets. | ||
| - | + Two beta sheets. | ||
| - | - One beta sheet. | ||
| - | - Two alpha helices. | ||
| - | - One alpha helix. | ||
| - | + One disulfide bond. | ||
| - | - Two disulfide bonds. | ||
| - | - A hydrophilic core. | ||
| - | + A hydrophobic core. | ||
| - | || | ||
| - | |||
| - | {Which CDRs contribute the most to antigen specificity? | ||
| - | |type="[]"} | ||
| - | - Light chain CDRs. | ||
| - | - Heavy chain CDRs. | ||
| - | - CDR1s. | ||
| - | - CDR2s. | ||
| - | + CDR3s. | ||
| - | - CDR4s. | ||
| - | || | ||
Revision as of 22:12, 13 July 2020
Antibody Quiz
You will get immediate feedback when you click Submit (at the bottom of the quiz). This quiz is offered to accompany the MHC structure tutorial at MolviZ.Org.
Suggestions to Eric Martz.
Educators are invited to copy this quiz into a Proteopedia page of your own, where you could delete some questions and add some of your own. (Click the tab edit this page at the top, then block and copy everything in the box. Paste that into the wikitext box of your own new page, and save the page. See Proteopedia:How to Make a Page.)
