User:Eric Martz/MHC Quiz

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{What does MHC class I do?
{What does MHC class I do?
|type="[]"}
|type="[]"}
-
- Removes worn out proteins.
 
- Presents peptides to CD4 "helper" T lymphocytes.
- Presents peptides to CD4 "helper" T lymphocytes.
+ Presents peptides to CD8 "cytotoxic" T lymphocytes.
+ Presents peptides to CD8 "cytotoxic" T lymphocytes.
+ Brings peptides from the proteasome to the cell surface.
+ Brings peptides from the proteasome to the cell surface.
- Brings peptides from the lysosome to the cell surface.
- Brings peptides from the lysosome to the cell surface.
 +
+ Presents shorter peptides than class II MHC.
 +
- Presents longer peptides than class II MHC.
 +
- Removes worn out proteins.
 +
- It makes antibody.
{What happens to cells that express little or no MHC class I?
{What happens to cells that express little or no MHC class I?
|type="[]"}
|type="[]"}
+ They are attacked by Natural Killer Cells.
+ They are attacked by Natural Killer Cells.
-
- They are attached by Cytotoxic T Lymphocytes.
+
- They are attacked by Cytotoxic T Lymphocytes.
- Nothing.
- Nothing.
- They are recycled by the lymphatic system.
- They are recycled by the lymphatic system.

Revision as of 23:02, 13 July 2020

Antibody Quiz

You will get immediate feedback when you click Submit (at the bottom of the quiz). This quiz is offered to accompany the MHC structure tutorial at MolviZ.Org.


In some cases, more than one answer may be correct.

1. What does "MHC" stand for?

Multiple Histocompatibility Complex.
Manifest Hybridoma Catalyst.
Major Histological Crevice.
Major Histocompatibility Complex.
Minor Histocompatibility Complex.

2. What does MHC class I do?

Presents peptides to CD4 "helper" T lymphocytes.
Presents peptides to CD8 "cytotoxic" T lymphocytes.
Brings peptides from the proteasome to the cell surface.
Brings peptides from the lysosome to the cell surface.
Presents shorter peptides than class II MHC.
Presents longer peptides than class II MHC.
Removes worn out proteins.
It makes antibody.

3. What happens to cells that express little or no MHC class I?

They are attacked by Natural Killer Cells.
They are attacked by Cytotoxic T Lymphocytes.
Nothing.
They are recycled by the lymphatic system.
They lose their ability to activate CD8 T lymphocytes.

4. How many polypeptide chains make up an MHC Class I molecule, not counting the antigenic peptide?

→

5. How many polypeptide chains make up the MHC I peptide-binding cleft, not counting the antigenic peptide?

→

An IgG1 molecule has a molecular weight of 150 kilo Daltons.

6.

What is the approximate molecular weight of one immunoglobulin domain in kD?
kD.
→ Twelve Ig domains in one IgG1 molecule. 150/12 = 12.5 kD.

Questions below may have more than one correct answer.


7. Antibody

Binds to antigen.
When bound to a microbe, recruits macrophages and other leukocytes to kill the microbes.
Defends us against infections.
Carries oxygen to tissues.
Is a hormone.
Strengthens bones.

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Eric Martz

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