DXP reductoisomerase
From Proteopedia
(Difference between revisions)
| Line 27: | Line 27: | ||
**[[4zqe]] – McDXR – ''Moraxella catarrhalis''<br /> | **[[4zqe]] – McDXR – ''Moraxella catarrhalis''<br /> | ||
**[[5kqo]], [[5kry]], [[5ks1]] – VvDXR – ''Vibrio vulnificus''<br /> | **[[5kqo]], [[5kry]], [[5ks1]] – VvDXR – ''Vibrio vulnificus''<br /> | ||
| + | **[[6mh4]] – SsDXR – ''Staphylococcus schleiferi''<br /> | ||
*DXP reductoisomerase binary complex | *DXP reductoisomerase binary complex | ||
| Line 42: | Line 43: | ||
**[[5krr]] – VvDXR + Mn<br /> | **[[5krr]] – VvDXR + Mn<br /> | ||
**[[5krv]] – VvDXR + Arg<br /> | **[[5krv]] – VvDXR + Arg<br /> | ||
| + | **[[6mh5]] – SsDXR + antibiotic<br /> | ||
*DXP reductoisomerase ternary complex | *DXP reductoisomerase ternary complex | ||
Revision as of 07:35, 20 July 2020
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3D Structures of DXP reductoisomerase
Updated on 20-July-2020
References
- ↑ Takahashi S, Kuzuyama T, Watanabe H, Seto H. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9879-84. PMID:9707569
- ↑ Jansson AM, Wieckowska A, Bjorkelid C, Yahiaoui S, Sooriyaarachchi S, Lindh M, Bergfors T, Dharavath S, Desroses M, Suresh S, Andaloussi M, Nikhil R, Sreevalli S, Srinivasa BR, Larhed M, Jones TA, Karlen A, Mowbray SL. DXR inhibition by potent mono- and disubstituted fosmidomycin analogues. J Med Chem. 2013 Aug 8;56(15):6190-9. doi: 10.1021/jm4006498. Epub 2013 Jul 17. PMID:23819803 doi:http://dx.doi.org/10.1021/jm4006498
