Endonuclease 3D structures

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(New page: ==3D structures of endonuclease== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *ENN-I **1bix - hENN – hum...)
Line 41: Line 41:
**[[4nsp]] – hENN catalytic domain<br />
**[[4nsp]] – hENN catalytic domain<br />
 +
**[[6oze]] – hENN (mutant) <br />
 +
**[[5aoy]] – mENN (mutant) <br />
 +
**[[6ozj]], [[6ozk]], [[6ozl]], [[6ozm]], [[6ozn]], [[6ozo]], [[6ozr]] – mENN + DNA <br />
 +
**[[6ozq]] – mENN (mutant) + DNA <br />
 +
**[[6ozp]], [[6ozs]] – mENN + DNA + RNA<br />
**[[1eni]], [[1enj]], [[1enk]], [[2end]] - T4ENN <br />
**[[1eni]], [[1enj]], [[1enk]], [[2end]] - T4ENN <br />
-
**[[1vas]] - T4ENN + DNA<br />
+
**[[1vas]], [[2fcc]] - T4ENN + DNA<br />
-
**[[2w35]], [[2w36]], [[4b20]] - TmENN + DNA – ''Thermotoga maritima''<br />
+
**[[3hd0]] - TmENN - ''Thermotoga maritima''<br />
-
**[[3hd0]] - TmENN <br />
+
**[[2w35]], [[2w36]], [[4b20]] - TmENN + DNA <br />
 +
**[[6ozf]], [[6ozg]] - TmENN (mutant) + DNA <br />
**[[3ga2]] - BsENN (mutant) – ''Bacillus subtilis''<br />
**[[3ga2]] - BsENN (mutant) – ''Bacillus subtilis''<br />
**[[3goc]] - ENN – ''Streptomyces avermitilis''<br />
**[[3goc]] - ENN – ''Streptomyces avermitilis''<br />
-
**[[2fcc]] – T4ENN + DNA<br />
+
**[[4xpu]] – EcENN <br />
 +
**[[6ozh]] - CiENN + DNA – ''Ciona intestinalis''<br />
 +
**[[6ozi]] – CiENN (mutant) + DNA<br />
*ENN-VII
*ENN-VII
Line 90: Line 98:
**[[4q2c]] - TteCas3 – ''Thermobaclum terrenum''<br />
**[[4q2c]] - TteCas3 – ''Thermobaclum terrenum''<br />
**[[4q2d]] - TteCas3 + ATP<br />
**[[4q2d]] - TteCas3 + ATP<br />
-
**[[3i4h]] – Cas4 - ''Pyrobaculum calidifontis''<br /
+
**[[3i4h]] – Cas4 - ''Pyrobaculum calidifontis''<br />
-
**[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br />
+
**[[6njy]] – Cas6 - ''Mahella australiensis''<br />
 +
**[[4qr0]], [[4qr1]], [[6o56]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br />
**[[4ilr]], [[3zfv]] – SsCas6 <br />
**[[4ilr]], [[3zfv]] – SsCas6 <br />
**[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br />
**[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br />
Line 119: Line 128:
**[[5xvp]], [[5xvo]], [[5xvn]] – Cas1 + Cas2 + DNA – ''Enterococcus faecalis''<br />
**[[5xvp]], [[5xvo]], [[5xvn]] – Cas1 + Cas2 + DNA – ''Enterococcus faecalis''<br />
**[[6qxt]], [[6qxf]] – GsCas1 (mutant) + EcCas2 + Csn2 + DNA – Cryo EM<br />
**[[6qxt]], [[6qxf]] – GsCas1 (mutant) + EcCas2 + Csn2 + DNA – Cryo EM<br />
 +
**[[6kdv]] – TtCas1 + DNA <br />
 +
**[[6opm]] – Cas1 + DNA – ''Methanosarcina mazei''<br />
**[[4ill]], [[4ilm]] – SsCas6 + RNA - ''Sulfolobus solfataricus''<br />
**[[4ill]], [[4ilm]] – SsCas6 + RNA - ''Sulfolobus solfataricus''<br />
**[[5uz9]] – PaCsa5f + Cas7f + Cas8f + anti-crispr protein + RNA - Cryo EM<br />
**[[5uz9]] – PaCsa5f + Cas7f + Cas8f + anti-crispr protein + RNA - Cryo EM<br />
Line 127: Line 138:
**[[2y8w]], [[2y8y]], [[3qrp]], [[3qrq]], [[2qrr]] – TtCas6e (Cse3) + RNA<br />
**[[2y8w]], [[2y8y]], [[3qrp]], [[3qrq]], [[2qrr]] – TtCas6e (Cse3) + RNA<br />
**[[2xli]], [[2xlj]], [[2xlk]], [[4al7]] – PaCas6f (Csy4) + RNA <br />
**[[2xli]], [[2xlj]], [[2xlk]], [[4al7]] – PaCas6f (Csy4) + RNA <br />
 +
**[[6vqv]], [[6w1x]] – PaCas6f (Csy4) + ACRF9 + Cys1 + Csy2 + Csy3 + RNA – Cryo EM<br />
 +
**[[6whi]] – PaCas6f (Csy4) + ACRF9 + Cys1 + Csy2 + Csy3 + RNA + DNA – Cryo EM<br />
 +
**[[6vqw]] – PaCas6f (Csy4) + ACRF8 + Cys1 + Csy2 + Csy3 + RNA – Cryo EM<br />
 +
**[[6vqx]] – PaCas6f (Csy4) + ACRF6 + Cys1 + Csy2 + Csy3 + RNA – Cryo EM<br />
**[[4al5]], [[4al6]] - PaCas6f (Csy4) (mutant) + RNA <br />
**[[4al5]], [[4al6]] - PaCas6f (Csy4) (mutant) + RNA <br />
**[[4zt0]] - SpCas9 + RNA <br />
**[[4zt0]] - SpCas9 + RNA <br />
**[[4zt9]] - SpCas9 (mutant) + RNA <br />
**[[4zt9]] - SpCas9 (mutant) + RNA <br />
-
**[[5f9r]] - SpCas9 + RNA + DNA<br />
+
**[[5f9r]], [[6k4p]], [[6k4q]], [[6o0x]], [[6o0y]], [[6o0z]] - SpCas9 + RNA + DNA<br />
-
**[[4oo8]], [[4un3]], [[4un4]], [[4un5]], [[5fw1]], [[5fw2]], [[5fw3]], [[5fq5]], [[5b2r]], [[5b2s]], [[5b2t]], [[5y36]], [[6ia6]] - SpCas9 (Csn1) (mutant) + RNA + DNA<br />
+
**[[4oo8]], [[4un3]], [[4un4]], [[4un5]], [[5fw1]], [[5fw2]], [[5fw3]], [[5fq5]], [[5b2r]], [[5b2s]], [[5b2t]], [[5y36]], [[6ia6]], [[6k3z]], [[6k4s]], [[6k4u]], [[6k57]] - SpCas9 (Csn1) (mutant) + RNA + DNA<br />
**[[5xbl]] - SpCas9 + associated protein + RNA <br />
**[[5xbl]] - SpCas9 + associated protein + RNA <br />
**[[6ifo]] - SpCas9 + AcriiA2 + RNA <br />
**[[6ifo]] - SpCas9 + AcriiA2 + RNA <br />
**[[5vw1]] - SpCas9 + AcriiA4 + RNA <br />
**[[5vw1]] - SpCas9 + AcriiA4 + RNA <br />
**[[6mcc]], [[5vzl]], [[6mcb]] - SpCas9 + AcriiA4 + RNA – Cryo EM<br />
**[[6mcc]], [[5vzl]], [[6mcb]] - SpCas9 + AcriiA4 + RNA – Cryo EM<br />
-
**[[5vgb]] - NmCas9 + AcriiC1 – Neisseria meningitidis <br />
+
**[[5vgb]] - NmCas9 + AcriiC1 – ''Neisseria meningitidis'' <br />
**[[6jdx]], [[6jdj]], [[6j9m]] - NmCas9 + AcriiC2 <br />
**[[6jdx]], [[6jdj]], [[6j9m]] - NmCas9 + AcriiC2 <br />
**[[6j9n]] - NmCas9 + AcriiC3 <br />
**[[6j9n]] - NmCas9 + AcriiC3 <br />
 +
**[[6jdq]] - NmCas9 + RNA <br />
 +
**[[6jdv]], [[6je3]], [[6jfu]], [[6kc8]] - NmCas9 + RNA + DNA<br />
 +
**[[6kc7]] - NmCas9 (mutant) + RNA + DNA<br />
 +
**[[6je9]] - NmCas9 + RNA + AcriiC3<br />
 +
**[[6je4]] - NmCas9 + RNA + DNA + AcriiC3<br />
 +
**[[6rj9]], [[6rja]], [[6rjg]] - StCas9 + RNA + DNA + AcriiA6 – ''Streptococcus thermophilus''<br />
 +
**[[6rjd]] - StCas9 + RNA + DNA<br />
**[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br />
**[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br />
**[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br />
**[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br />
Line 187: Line 209:
**[[1bam]] – BaENN – ''Bacillus amyloliquefaciens''<br />
**[[1bam]] – BaENN – ''Bacillus amyloliquefaciens''<br />
**[[1bhm]], [[3bam]], [[2bam]], [[1esg]] - BaENN + DNA
**[[1bhm]], [[3bam]], [[2bam]], [[1esg]] - BaENN + DNA
 +
 +
*Bax1 ENN
 +
 +
**[[6p4o]], [[6p4w]] – StENN + DNA-dependent ATPase XPBII – ''Sulfurisphera tokidaii''<br />
 +
**[[6p4o]] – StENN + DNA-dependent ATPase XPBII + DNA<br />
 +
**[[6p66]] – AfENN + Rad25<br />
*Bbvci ENN
*Bbvci ENN
Line 291: Line 319:
**[[5fv7]] - hENN + inhibitor<br />
**[[5fv7]] - hENN + inhibitor<br />
**[[1ul1]] - hENN + PCNA <br />
**[[1ul1]] - hENN + PCNA <br />
 +
**[[6tnz]] - hENN in processive polymerase – Cryo EM <br />
**[[1mc8]] - PhENN (mutant) <br />
**[[1mc8]] - PhENN (mutant) <br />
**[[3ory]]– ENN – ''Desulfurococcus amylolyticus''<br />
**[[3ory]]– ENN – ''Desulfurococcus amylolyticus''<br />
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**[[4xlg]] – CgENN SLX1 (mutant)+SLX4 subunits<br />
**[[4xlg]] – CgENN SLX1 (mutant)+SLX4 subunits<br />
**[[4zdt]] – fyENN SLX1+SLX4 subunits<br />
**[[4zdt]] – fyENN SLX1+SLX4 subunits<br />
 +
**[[6seh]] – ThtENN SLX1 (mutant)+SLX4 subunits – ''Thielavia terrestris''<br />
 +
**[[6sei]] – ThtENN SLX1 (mutant)+SLX4 subunits + DNA<br />
*BfiI ENN
*BfiI ENN
Line 404: Line 435:
**[[1z00]], [[2a1j]] - hENN C terminal + DNA excision repair protein<br />
**[[1z00]], [[2a1j]] - hENN C terminal + DNA excision repair protein<br />
 +
**[[6sxa]] - hENN + DNA excision repair protein – Cryo EM<br />
 +
**[[6sxb]] - hENN + DNA excision repair protein + DNA – Cryo EM<br />
**[[2aq0]] – hENN residues 823-905 – NMR<br />
**[[2aq0]] – hENN residues 823-905 – NMR<br />
**[[2kn7]] – hENN residues 823-905 + DNA – NMR<br />
**[[2kn7]] – hENN residues 823-905 + DNA – NMR<br />
Line 418: Line 451:
**[[5ed0]], [[5ecy]] – SfENN – ''Shigella flexneri''<br />
**[[5ed0]], [[5ecy]] – SfENN – ''Shigella flexneri''<br />
**[[5ecy]], [[5ecw]], [[5ecd]] – SfENN (mutant)<br />
**[[5ecy]], [[5ecw]], [[5ecd]] – SfENN (mutant)<br />
 +
**[[6ifc]] – StENN + Vapb – ''Salmonella typhimurium''<br />
 +
**[[6ifm]] – StENN + Vapb + DNA<br />
*Muts2 ENN
*Muts2 ENN
Line 430: Line 465:
*ENN G
*ENN G
 +
**[[6njt]] – mENN (mutant)<br />
 +
**[[6nju]] – mENN (mutant) + DNA<br />
**[[5gkc]], [[4qn0]] – CeENN (mutant) – ''Caenorhabdfitis elegans''<br />
**[[5gkc]], [[4qn0]] – CeENN (mutant) – ''Caenorhabdfitis elegans''<br />
**[[5gkp]] – CeENN (mutant) + DNA <br />
**[[5gkp]] – CeENN (mutant) + DNA <br />
Line 436: Line 473:
**[[5ybb]] – ENN + R-M system + DNA – ''Caldanaerobacter subterraneus'' <br />
**[[5ybb]] – ENN + R-M system + DNA – ''Caldanaerobacter subterraneus'' <br />
- 
-
*ENN V
 
- 
-
**[[5aoy]] – mENN (mutant) <br />
 
-
**[[4xpu]] – EcENN <br />
 
*Apurinic-apyrimidinic ENN
*Apurinic-apyrimidinic ENN
**[[5cfg]], [[6mk3]], [[6mkk]], [[6mkm]], [[6mko]] – hENN <br />
**[[5cfg]], [[6mk3]], [[6mkk]], [[6mkm]], [[6mko]] – hENN <br />
-
**[[5dff]], [[5dfh]], [[5dfi]], [[5dfj]], [[5dg0]], [[5wn5]], [[5wn4]], [[5wn3]], [[5wn2]], [[5wn1]], [[5wn0]], [[6bos]] – hENN + DNA<br />
+
**[[5dff]], [[5dfh]], [[5dfi]], [[5dfj]], [[5dg0]], [[5wn5]], [[5wn4]], [[5wn3]], [[5wn2]], [[5wn1]], [[5wn0]], [[6bos]], [[6w3l]], [[6w3n]], [[6w3q]], [[6w3u]] – hENN + DNA<br />
-
**[[6bot]], [[6boq]], [[6bor]], [[6bou]], [[6bov]], [[6bow]] – hENN (mutant) + DNA<br />
+
**[[6bot]], [[6boq]], [[6bor]], [[6bou]], [[6bov]], [[6bow]], [[6p93]], [[6p94]], [[6w0q]], [[6w43]], [[6w4i]], [[6w4t]] – hENN (mutant) + DNA<br />
 +
 
 +
*Restriction ENN Pfoi
 +
 
 +
**[[6ek1]] – PfENN – ''Pseudomons fluorescens'' <br />
 +
**[[6eko]] – PfENN (mutant) + DNA<br />
 +
 
 +
*Restriction ENN Hhai
 +
 
 +
**[[6uke]], [[6ukf]], [[6ukg]], [[6ukh]], [[6uki]] – ENN + DNA – ''Haemophilus parahaemolyticus'' <br />
*'''Intron-encoded endonuclease'''
*'''Intron-encoded endonuclease'''

Revision as of 09:27, 21 July 2020

3D structures of endonuclease

Updated on 21-July-2020

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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