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Ephrin

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**[[1shx]] – mEph receptor-binding domain – mouse<br />
**[[1shx]] – mEph receptor-binding domain – mouse<br />
**[[1shw]] – mEph residues 88-225 + Eph type B receptor 2 <br />
**[[1shw]] – mEph residues 88-225 + Eph type B receptor 2 <br />
 +
 +
*Ephrin-B1
 +
 +
**[[6thg]] – hEph extracellular domain 27-170 + glycoprotein <br />
 +
**[[6p7s]] – mEph extracellular domain + glycoprotein <br />
*Ephrin-B2
*Ephrin-B2
**[[2i85]] – hEph residues 1-142 – NMR<br />
**[[2i85]] – hEph residues 1-142 – NMR<br />
-
**[[2wo2]], [[3gxu]] – hEph receptor-binding domain + Eph type A receptor 4 <br />
+
**[[2wo2]], [[3gxu]] – hEph extracellular domain + Eph type A receptor 4 <br />
-
**[[4uf7]] – hEph receptor-binding domain + glycoprotein <br />
+
**[[4uf7]], [[6pdl]] – hEph extracellular domain + glycoprotein <br />
-
**[[2vsk]], [[2vsm]] – hEph receptor-binding domain + virus hemagglutinin neuraminidase <br />
+
**[[2vsk]], [[2vsm]] – hEph extracellular domain + virus hemagglutinin neuraminidase <br />
**[[1iko]] – mEph ectodomain <br />
**[[1iko]] – mEph ectodomain <br />
-
**[[1kgy]] – mEph receptor-binding domain + Eph type B receptor 2 <br />
+
**[[1kgy]] – mEph extracellular domain + Eph type B receptor 2 <br />
-
**[[2hle]] – mEph receptor-binding domain + Eph type B receptor 4 <br />
+
**[[2hle]] – mEph extracellular domain + Eph type B receptor 4 <br />
 +
**[[6p7y]] – mEph extracellular domain + glycoprotein <br />
*Ephrin-B3
*Ephrin-B3

Revision as of 09:20, 22 July 2020

Structure of glycosylated human ephrin-A5 receptor-binding domain (green) complex with ephrin type A receptor 2 (cyan) (PDB code 3mx0).

Drag the structure with the mouse to rotate

3D structures of ephrin

Updated on 22-July-2020


References

  1. ↑ Egea J, Klein R. Bidirectional Eph-ephrin signaling during axon guidance. Trends Cell Biol. 2007 May;17(5):230-8. Epub 2007 Apr 8. PMID:17420126 doi:http://dx.doi.org/10.1016/j.tcb.2007.03.004
  2. ↑ Himanen JP, Yermekbayeva L, Janes PW, Walker JR, Xu K, Atapattu L, Rajashankar KR, Mensinga A, Lackmann M, Nikolov DB, Dhe-Paganon S. Architecture of Eph receptor clusters. Proc Natl Acad Sci U S A. 2010 May 26. PMID:20505120

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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