2ye8

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==HSP90 inhibitors and drugs from fragment and virtual screening==
==HSP90 inhibitors and drugs from fragment and virtual screening==
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<StructureSection load='2ye8' size='340' side='right' caption='[[2ye8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='2ye8' size='340' side='right'caption='[[2ye8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ye8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YE8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ye8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YE8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YE8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2D3:METHYL+3-ISOXAZOL-5-YL-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE'>2D3</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2D3:METHYL+3-ISOXAZOL-5-YL-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE'>2D3</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cdd|2cdd]], [[1yes|1yes]], [[1uy9|1uy9]], [[1byq|1byq]], [[2bsm|2bsm]], [[1osf|1osf]], [[2wi3|2wi3]], [[1uy8|1uy8]], [[2bug|2bug]], [[2wi4|2wi4]], [[2uwd|2uwd]], [[2wi7|2wi7]], [[2xhx|2xhx]], [[2bt0|2bt0]], [[1yer|1yer]], [[2xdu|2xdu]], [[1uyg|1uyg]], [[2bz5|2bz5]], [[2ccu|2ccu]], [[2xds|2xds]], [[2xdx|2xdx]], [[2ccs|2ccs]], [[2xk2|2xk2]], [[1uyi|1uyi]], [[2xjj|2xjj]], [[1uyf|1uyf]], [[1yc3|1yc3]], [[1uyd|1uyd]], [[2byi|2byi]], [[2wi2|2wi2]], [[2xdl|2xdl]], [[2vci|2vci]], [[1uy6|1uy6]], [[2wi1|2wi1]], [[2vcj|2vcj]], [[1yc4|1yc4]], [[2xjx|2xjx]], [[2fwz|2fwz]], [[2xdk|2xdk]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[1uyh|1uyh]], [[2xjg|2xjg]], [[2cct|2cct]], [[2fwy|2fwy]], [[1uye|1uye]], [[1uyl|1uyl]], [[2wi6|2wi6]], [[2xab|2xab]], [[1yc1|1yc1]], [[2xht|2xht]], [[1uy7|1uy7]], [[2xhr|2xhr]], [[1uyc|1uyc]], [[1yet|1yet]], [[2jjc|2jjc]], [[2byh|2byh]], [[2wi5|2wi5]], [[2yee|2yee]], [[2ye2|2ye2]], [[2ye9|2ye9]], [[2yeb|2yeb]], [[2ye7|2ye7]], [[2ye4|2ye4]], [[2yej|2yej]], [[2yec|2yec]], [[2ye5|2ye5]], [[2yea|2yea]], [[2yeh|2yeh]], [[2ye6|2ye6]], [[2yed|2yed]], [[2yei|2yei]], [[2yeg|2yeg]], [[2yef|2yef]], [[2ye3|2ye3]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cdd|2cdd]], [[1yes|1yes]], [[1uy9|1uy9]], [[1byq|1byq]], [[2bsm|2bsm]], [[1osf|1osf]], [[2wi3|2wi3]], [[1uy8|1uy8]], [[2bug|2bug]], [[2wi4|2wi4]], [[2uwd|2uwd]], [[2wi7|2wi7]], [[2xhx|2xhx]], [[2bt0|2bt0]], [[1yer|1yer]], [[2xdu|2xdu]], [[1uyg|1uyg]], [[2bz5|2bz5]], [[2ccu|2ccu]], [[2xds|2xds]], [[2xdx|2xdx]], [[2ccs|2ccs]], [[2xk2|2xk2]], [[1uyi|1uyi]], [[2xjj|2xjj]], [[1uyf|1uyf]], [[1yc3|1yc3]], [[1uyd|1uyd]], [[2byi|2byi]], [[2wi2|2wi2]], [[2xdl|2xdl]], [[2vci|2vci]], [[1uy6|1uy6]], [[2wi1|2wi1]], [[2vcj|2vcj]], [[1yc4|1yc4]], [[2xjx|2xjx]], [[2fwz|2fwz]], [[2xdk|2xdk]], [[2c2l|2c2l]], [[1uyk|1uyk]], [[1uyh|1uyh]], [[2xjg|2xjg]], [[2cct|2cct]], [[2fwy|2fwy]], [[1uye|1uye]], [[1uyl|1uyl]], [[2wi6|2wi6]], [[2xab|2xab]], [[1yc1|1yc1]], [[2xht|2xht]], [[1uy7|1uy7]], [[2xhr|2xhr]], [[1uyc|1uyc]], [[1yet|1yet]], [[2jjc|2jjc]], [[2byh|2byh]], [[2wi5|2wi5]], [[2yee|2yee]], [[2ye2|2ye2]], [[2ye9|2ye9]], [[2yeb|2yeb]], [[2ye7|2ye7]], [[2ye4|2ye4]], [[2yej|2yej]], [[2yec|2yec]], [[2ye5|2ye5]], [[2yea|2yea]], [[2yeh|2yeh]], [[2ye6|2ye6]], [[2yed|2yed]], [[2yei|2yei]], [[2yeg|2yeg]], [[2yef|2yef]], [[2ye3|2ye3]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ye8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ye8 OCA], [http://pdbe.org/2ye8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ye8 RCSB], [http://www.ebi.ac.uk/pdbsum/2ye8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ye8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ye8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ye8 OCA], [http://pdbe.org/2ye8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ye8 RCSB], [http://www.ebi.ac.uk/pdbsum/2ye8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ye8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
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*[[Heat Shock Proteins|Heat Shock Proteins]]
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Baker, L M]]
[[Category: Baker, L M]]
[[Category: Hubbard, R E]]
[[Category: Hubbard, R E]]

Revision as of 12:46, 22 July 2020

HSP90 inhibitors and drugs from fragment and virtual screening

PDB ID 2ye8

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