Sandbox 20006

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Left side Proteopedia Morph (10 linear steps, no alignment, C-alpha atoms)
Left side Proteopedia Morph (10 linear steps, no alignment, C-alpha atoms)
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Right side Karsten/Eric Morph: 6ZGG (an open conformation) was aligned with 6ZGI (a closed conformation) using the Iterative Magic Fit of Swiss-PDB-Viewer. This aligned 1,828 alpha carbons (mainly the core of the structure, regions S???) with RMSD 1.34 Å. The closed model was morphed (linear interpolation) to the open model using the server provided by Karsten Theis, requesting 8 intermediate frames. The resulting 10-frame PDB file was loaded into the Jmol Java application. The alpha carbons were selected ("select *.ca") and written into a separate file, which was uploaded to Proteopedia for use in the above morph scenes: Image:Morf-6zgi-to-6zgg-alpha-carbons-only.pdb.
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Right side Karsten/Eric Morph: Iterative Magic Fit of Swiss-PDB-Viewer.
<Structure load='' size='350' frame='true' align='right' caption='Insert caption here' scene='85/857154/6zgi_to_6zgg/4' />
<Structure load='' size='350' frame='true' align='right' caption='Insert caption here' scene='85/857154/6zgi_to_6zgg/4' />

Revision as of 08:08, 26 July 2020

Your Heading Here (maybe something like 'Structure')

Morph showing the transition of SARS-CoV-2 spike protein from its closed to open conformation induced by proteolytic cleavage by furin, see [Details of this morph]

Drag the structure with the mouse to rotate

References

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