Ferric hydroxamate uptake receptor

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	*FhuD2		*FhuD2
-	**[[4fna]] – SaFhuA – ''Staphylococcus aureus''<br />	+	**[[4fna]] – SaFhuD2 – ''Staphylococcus aureus''<br />
-	**[[4fil]] – SaFhuA (mutant) + ferrioxamine + Zn <br />	+	**[[4fil]] – SaFhuD2 (mutant) + ferrioxamine + Zn <br />
	* FhuA		* FhuA

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Revision as of 08:52, 27 July 2020

spinqualitylabelsall models E. coli FhuA complex with ferrichrome and Fe+3 ion (orange) (PDB code 1by5). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Ferric hydroxamate uptake receptor proteins FhuA, FhuB, FhuC and FhuD are involved in the uptake of the hydroxamate ferrichrome siderophore for use as an iron source[1]. For more details see FhuD. Disease Haemophilus parasuis uses Fhu to capture iron and is the cause of the Glasser disease in pigs. Structural highlights includes (in cyan) and contains Fe atom. The (Hydrophobic, Polar).[2]

3D structures of Ferric hydroxamate uptake receptor

Updated on 27-July-2020

References

1. ↑ Forman S, Nagiec MJ, Abney J, Perry RD, Fetherston JD. Analysis of the aerobactin and ferric hydroxamate uptake systems of Yersinia pestis. Microbiology. 2007 Jul;153(Pt 7):2332-41. PMID:17600077 doi:http://dx.doi.org/10.1099/mic.0.2006/004275-0
2. ↑ Locher KP, Rees B, Koebnik R, Mitschler A, Moulinier L, Rosenbusch JP, Moras D. Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell. 1998 Dec 11;95(6):771-8. PMID:9865695