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2zlg

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==The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase==
==The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase==
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<StructureSection load='2zlg' size='340' side='right' caption='[[2zlg]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
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<StructureSection load='2zlg' size='340' side='right'caption='[[2zlg]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zlg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZLG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zlg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZLG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZLG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRT:(5R,9S,12S,15S,18S,21S)-21-BENZYL-12,18-BIS(CARBOXYMETHYL)-15-CYCLOHEXYL-1-(9H-FLUOREN-9-YL)-4-METHYL-9-(2-METHYLPROPYL)-3,6,10,13,16,19-HEXAOXO-5-PHENYL-2-OXA-4,8,11,14,17,20-HEXAAZADOCOSAN-22-OIC+ACID'>MRT</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRT:(5R,9S,12S,15S,18S,21S)-21-BENZYL-12,18-BIS(CARBOXYMETHYL)-15-CYCLOHEXYL-1-(9H-FLUOREN-9-YL)-4-METHYL-9-(2-METHYLPROPYL)-3,6,10,13,16,19-HEXAOXO-5-PHENYL-2-OXA-4,8,11,14,17,20-HEXAAZADOCOSAN-22-OIC+ACID'>MRT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zlf|2zlf]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zlf|2zlf]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlg OCA], [http://pdbe.org/2zlg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zlg RCSB], [http://www.ebi.ac.uk/pdbsum/2zlg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zlg OCA], [http://pdbe.org/2zlg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zlg RCSB], [http://www.ebi.ac.uk/pdbsum/2zlg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zlg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
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*[[Ribonucleotide reductase|Ribonucleotide reductase]]
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Atcc 18824]]
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[[Category: Large Structures]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Ribonucleoside-diphosphate reductase]]
[[Category: Cooperman, B S]]
[[Category: Cooperman, B S]]

Revision as of 12:06, 29 July 2020

The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase

PDB ID 2zlg

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