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- | | + | #REDIRECT [[6w4m]] This PDB entry is obsolete and replaced by 6w4m |
- | ==CRYSTAL STRUCTURE OF THE ADCC-POTENT, WEAKLY NEUTRALIZING HIV ENV CO-RECEPTOR BINDING SITE ANTIBODY N12-I2 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 AND M48U1==
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- | <StructureSection load='5uwe' size='340' side='right'caption='[[5uwe]], [[Resolution|resolution]] 3.19Å' scene=''>
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- | == Structural highlights ==
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- | <table><tr><td colspan='2'>[[5uwe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UWE FirstGlance]. <br>
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- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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- | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPR:D-PROLINE'>DPR</scene>, <scene name='pdbligand=MPT:BETA-MERCAPTOPROPIONIC+ACID'>MPT</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TYS:O-SULFO-L-TYROSINE'>TYS</scene>, <scene name='pdbligand=U2X:O-(CYCLOHEXYLMETHYL)-L-TYROSINE'>U2X</scene></td></tr>
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- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qeg|3qeg]]</td></tr>
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- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HIV-1 Env ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
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- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uwe OCA], [http://pdbe.org/5uwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uwe RCSB], [http://www.ebi.ac.uk/pdbsum/5uwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uwe ProSAT]</span></td></tr>
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- | </table>
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- | ==See Also==
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- | *[[Antibody 3D structures|Antibody 3D structures]]
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- | *[[Gp120 3D structures|Gp120 3D structures]]
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- | __TOC__
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- | </StructureSection>
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- | [[Category: Human]]
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- | [[Category: Large Structures]]
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- | [[Category: Gohain, N]]
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- | [[Category: Pazgier, M]]
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- | [[Category: Tolbert, W D]]
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- | [[Category: Adcc and neutralizing anti-hiv-1 env antibody n12-i2]]
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- | [[Category: Cd4i antibody]]
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- | [[Category: Clade a/e 93th057]]
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- | [[Category: Fab fragment]]
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- | [[Category: Hiv-1 gp120]]
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- | [[Category: Immune system]]
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- | [[Category: Viral protein-immune system complex]]
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