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5ktw
From Proteopedia
(Difference between revisions)
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==CREBBP bromodomain in complex with Cpd 44 (3-((5-acetyl-1-(cyclopropylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)amino)-N-isopropylbenzamide)== | ==CREBBP bromodomain in complex with Cpd 44 (3-((5-acetyl-1-(cyclopropylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)amino)-N-isopropylbenzamide)== | ||
| - | <StructureSection load='5ktw' size='340' side='right' caption='[[5ktw]], [[Resolution|resolution]] 1.09Å' scene=''> | + | <StructureSection load='5ktw' size='340' side='right'caption='[[5ktw]], [[Resolution|resolution]] 1.09Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ktw]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KTW OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5ktw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KTW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KTW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6XG:3-[[1-(CYCLOPROPYLMETHYL)-5-ETHANOYL-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDIN-3-YL]AMINO]-~{N}-PROPAN-2-YL-BENZAMIDE'>6XG</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6XG:3-[[1-(CYCLOPROPYLMETHYL)-5-ETHANOYL-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDIN-3-YL]AMINO]-~{N}-PROPAN-2-YL-BENZAMIDE'>6XG</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ktx|5ktx]], [[5ku3|5ku3]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ktx|5ktx]], [[5ku3|5ku3]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CREBBP, CBP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ktw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ktw OCA], [http://pdbe.org/5ktw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ktw RCSB], [http://www.ebi.ac.uk/pdbsum/5ktw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ktw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5ktw" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5ktw" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[CREB-binding protein 3D structures|CREB-binding protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Histone acetyltransferase]] | [[Category: Histone acetyltransferase]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Boenig, G]] | [[Category: Boenig, G]] | ||
[[Category: Murray, J M]] | [[Category: Murray, J M]] | ||
[[Category: Crebbp bromodomain]] | [[Category: Crebbp bromodomain]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 06:34, 5 August 2020
CREBBP bromodomain in complex with Cpd 44 (3-((5-acetyl-1-(cyclopropylmethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)amino)-N-isopropylbenzamide)
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