5la7

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==Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355==
==Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355==
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<StructureSection load='5la7' size='340' side='right' caption='[[5la7]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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<StructureSection load='5la7' size='340' side='right'caption='[[5la7]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5la7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LA7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LA7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5la7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LA7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LA7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6S6:(1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic+acid'>6S6</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6S6:(1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic+acid'>6S6</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Heparanase Heparanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.166 3.2.1.166] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Heparanase Heparanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.166 3.2.1.166] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5la7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5la7 OCA], [http://pdbe.org/5la7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5la7 RCSB], [http://www.ebi.ac.uk/pdbsum/5la7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5la7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5la7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5la7 OCA], [http://pdbe.org/5la7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5la7 RCSB], [http://www.ebi.ac.uk/pdbsum/5la7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5la7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</StructureSection>
</StructureSection>
[[Category: Heparanase]]
[[Category: Heparanase]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Davies, G J]]
[[Category: Davies, G J]]
[[Category: Jin, Y]]
[[Category: Jin, Y]]

Revision as of 07:04, 5 August 2020

Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355

PDB ID 5la7

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