Glutamate receptor 3D structures

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*GluR domains: ATD 1-393; LBD 394-544; TMD 545-908
+
*GluR domains: ATD 1-393; LBD 394-544+684-821; TMD 545-908; extracellular 24-840
*Ionotropic glutamate receptor 0
*Ionotropic glutamate receptor 0
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**[[5fth]], [[5fti]], [[5ns9]] - rIGluR2 LBD (mutant) + Glu<br />
**[[5fth]], [[5fti]], [[5ns9]] - rIGluR2 LBD (mutant) + Glu<br />
**[[5kk2]], [[5vov]], [[5vou]], [[5vot]] - rIGluR2 + calcium channel γ2 subunit – Cryo-EM<br />
**[[5kk2]], [[5vov]], [[5vou]], [[5vot]] - rIGluR2 + calcium channel γ2 subunit – Cryo-EM<br />
 +
**[[6ucb]], [[6ud4]], [[6ud8]] - rIGluR2 + CNIH-3 + antagonist – Cryo-EM<br />
-
*''GluR2 positive allosteric modulator complex''
+
*''GluR2 allosteric modulator complex''
**[[2xhd]], [[5h8s]] - hIGluR2 LBD + positive allosteric modulator + Glu<br />
**[[2xhd]], [[5h8s]] - hIGluR2 LBD + positive allosteric modulator + Glu<br />
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**[[1mm6]], [[1mm7]], [[6hca]] - rIGluR2 LBD + positive allosteric modulator<br />
**[[1mm6]], [[1mm7]], [[6hca]] - rIGluR2 LBD + positive allosteric modulator<br />
**[[3ik6]] - rIGluR2 + Duiril + Glu<br />
**[[3ik6]] - rIGluR2 + Duiril + Glu<br />
 +
**[[6ruq]] - rIGluR2 extracellular domain (mutant) + antagonist + negative allosteric modulator<br />
*''GluR2 antagonist complex''
*''GluR2 antagonist complex''
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**[[6fqh]], [[6fqg]] - hIGluR2 LBD (mutant) + antagonist<br />
**[[6fqh]], [[6fqg]] - hIGluR2 LBD (mutant) + antagonist<br />
**[[3kgc]], [[3kg2]], [[2cmo]] - rIGluR2 LBD + antagonist + Glu<br />
**[[3kgc]], [[3kg2]], [[2cmo]] - rIGluR2 LBD + antagonist + Glu<br />
-
**[[4u4g]] - rIGluR2 + antagonist<br />
+
**[[4u4g]], [[6u5s]], [[6u6i]] - rIGluR2 + antagonist<br />
A [[Glutamate receptor (GluA2)|topic page]] describing in detail the [[Glutamate receptor (GluA2)|GluA2 structure described in 3kg2]]<br />
A [[Glutamate receptor (GluA2)|topic page]] describing in detail the [[Glutamate receptor (GluA2)|GluA2 structure described in 3kg2]]<br />
-
**[[3h03]], [[3h06]], [[3b7d]], [[1n0t]], [[1ftl]], [[3tza]], [[3ua8]], [[4isu]], [[5cbs]], [[5cbr]], [[4yma]] - rIGluR2 LBD + antagonist<br />
+
**[[3h03]], [[3h06]], [[3b7d]], [[1n0t]], [[1ftl]], [[3tza]], [[3ua8]], [[4isu]], [[5cbs]], [[5cbr]], [[4yma]], [[6yk2]], [[6yk3]], [[6yk4]], [[6yk5]], [[6yk6]] - rIGluR2 LBD + antagonist<br />
**[[1lb9]], [[4l17]], [[4u21]], [[4u22]], [[4u23]], [[5kbv]] - rIGluR2 LBD (mutant) + antagonist<br />
**[[1lb9]], [[4l17]], [[4u21]], [[4u22]], [[4u23]], [[5kbv]] - rIGluR2 LBD (mutant) + antagonist<br />
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**[[4uqk]], [[4uqj]], [[4uq6]] - rIGluR2 + quisqualate – Cryo EM<br />
**[[4uqk]], [[4uqj]], [[4uq6]] - rIGluR2 + quisqualate – Cryo EM<br />
**[[4wxj]] - DmIGluR2 LBD + Glu<br />
**[[4wxj]] - DmIGluR2 LBD + Glu<br />
 +
 +
*Ionotropic glutamate receptor 3.3
 +
 +
**[[6r88]] – AtIGluR3.3 LBD – ''Arabidopsis thaliana''<br />
 +
**[[6r85]] – AtIGluR3.3 LBD + Glu <br />
 +
**[[6r89]], [[6r8a]] – AtIGluR3.3 LBD + amino acid <br />
*Ionotropic glutamate receptor δ
*Ionotropic glutamate receptor δ
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**[[5kc8]] – hIGluRδ2 ATD<br />
**[[5kc8]] – hIGluRδ2 ATD<br />
**[[5kc9]] – IGluRδ1 C-terminal - mouse <br />
**[[5kc9]] – IGluRδ1 C-terminal - mouse <br />
-
**[[5l2e]] – rIGluRδ2 <br />
+
**[[6ksp]], [[6kss]] – rIGluRδ1 extracellular domain – Cryo EM<br />
 +
**[[5l2e]] – rIGluRδ2 extracellular domain<br />
 +
**[[6lu9]] – rIGluRδ2 extracellular domain – Cryo EM<br />
**[[5cc2]] – rIGluRδ2 LBD + agonist<br />
**[[5cc2]] – rIGluRδ2 LBD + agonist<br />
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**[[6qkz]], [[6qkc]] – rIGluR1 + rGluR2 + calcium channel g-8 – Cryo EM <br />
**[[6qkz]], [[6qkc]] – rIGluR1 + rGluR2 + calcium channel g-8 – Cryo EM <br />
-
**[[6njl]] – rIGluR1 + rGluR2 + calcium channel g-8 + auxiliary protein + antibody – Cryo EM <br />
+
**[[6njl]] – rIGluR1 + rGluR2 + calcium channel g-8 + SCFV + auxiliary protein + antibody – Cryo EM <br />
 +
**[[6ovd]], [[6ove]] – rIGluR1 + rGluR2 residues 415-821 + antagonist<br />
*Ionotropic glutamate receptor 1+2+3
*Ionotropic glutamate receptor 1+2+3
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**[[3olz]] – rGluK3 ATD<br />
**[[3olz]] – rGluK3 ATD<br />
-
**[[6fjz]], [[6fjy]] - rGluK3 residues 32-840 (mutant)<br />
+
**[[6fjz]], [[6fjy]] - rGluK3 extracellular domain (mutant)<br />
 +
**[[6kzm]], [[6l6f]] - rGluK3 extracellular domain (mutant) – Cryo EM<br />
**[[3s9e]], [[3u93]], [[3u94]], [[4mh5]] – rGluK3 LBD + Glu<br />
**[[3s9e]], [[3u93]], [[3u94]], [[4mh5]] – rGluK3 LBD + Glu<br />
**[[5nf6]] - rGluK3 LBD + Glu analog<br />
**[[5nf6]] - rGluK3 LBD + Glu analog<br />
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**[[5h8f]] – hNMDAR LBD <br />
**[[5h8f]] – hNMDAR LBD <br />
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**[[6mmx]], [[6mmw]], [[6mmv]], [[6mmu]], [[6mmt]], [[6mms]], [[6mmr]], [[6mmp]], [[6mmn]], [[6mmm]], [[6mml]], [[6mmk]], [[6mmj]], [[6mmi]], [[6mmh]], [[6mmg]], [[6mmb]], [[6mma]], [[6mm9]], [[6irh]], [[6irg]], [[6irf]], [[6ira]] – rNMDAR ATD+LBD+TMD – Cryo EM <br />
+
**[[6mmx]], [[6mmw]], [[6mmv]], [[6mmu]], [[6mmt]], [[6mms]], [[6mmr]], [[6mmp]], [[6mmn]], [[6mmm]], [[6mml]], [[6mmk]], [[6mmj]], [[6mmi]], [[6mmh]], [[6mmg]], [[6mmb]], [[6mma]], [[6mm9]], [[6irh]], [[6irg]], [[6irf]], [[6ira]], [[6mm9]], [[6mma]], [[6mmb]], [[6mmg]], [[6mmh]], [[6mmi]], [[6mmj]], [[6mmk]], [[6mml]], [[6mmm]], [[6mmn]], [[6mmp]], [[6mmr]], [[6mms]], [[6mmt]], [[6mmu]], [[6mmv]], [[6mmw]], [[6mmx]] – rNMDAR – Cryo EM <br />
**[[4nf4]], [[4nf5]], [[4nf6]], [[4nf8]], [[2a5t]] – rNMDAR LBD <br />
**[[4nf4]], [[4nf5]], [[4nf6]], [[4nf8]], [[2a5t]] – rNMDAR LBD <br />
**[[5tpz]] – XlNMDAR ATD <br />
**[[5tpz]] – XlNMDAR ATD <br />
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**[[5vij]], [[5vii]], [[5vih]], [[5dex]], [[5u8c]] – rNMDAR LBD + antagonist<br />
**[[5vij]], [[5vii]], [[5vih]], [[5dex]], [[5u8c]] – rNMDAR LBD + antagonist<br />
**[[5vij]], [[5vii]], [[5vih]], [[5u8c]] – rNMDAR LBD+TMD + antagonist<br />
**[[5vij]], [[5vii]], [[5vih]], [[5u8c]] – rNMDAR LBD+TMD + antagonist<br />
 +
**[[6usu]] – rNMDAR LBD + antagonist + Glu<br />
 +
**[[6usv]] – rNMDAR LBD + antagonist + Gly<br />
 +
**[[6uz6]] – rNMDAR LBD (mutant) + antagonist + Glu + Gly<br />
 +
**[[6uzr]], [[6uzw]] – rNMDAR LBD + antagonist + Gly<br />
 +
**[[6uzg]], [[6uzx]] – rNMDAR LBD (mutant) + antagonist + Gly<br />
**[[5jty]], [[5fxj]] – rNMDAR + agonist<br />
**[[5jty]], [[5fxj]] – rNMDAR + agonist<br />
**[[5tq0]], [[5tq2]] – rNMDAR LBD + antibody<br />
**[[5tq0]], [[5tq2]] – rNMDAR LBD + antibody<br />
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*''NMDAR subunit NR1+NR2B''
*''NMDAR subunit NR1+NR2B''
-
**[[6cna]] – rNMDAR ATD+LBD+TMD – Cryo EM <br />
+
**[[6cna]] – rNMDAR – Cryo EM <br />
**[[5tpz]] – rNMDAR LBD <br />
**[[5tpz]] – rNMDAR LBD <br />
 +
**[[6wi0]] – rNMDAR + antagonist – Cryo EM <br />
**[[4pe5]], [[4tll]], [[4tlm]] – rNMDAR (mutants)<br />
**[[4pe5]], [[4tll]], [[4tlm]] – rNMDAR (mutants)<br />
**[[5b3j]] – XlNMDAR1 ATD (mutant) + rNMDAR2B ATD (mutant) + antibody<br />
**[[5b3j]] – XlNMDAR1 ATD (mutant) + rNMDAR2B ATD (mutant) + antibody<br />
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**[[5ipu]], [[6e7x]], [[6e7w]], [[6e7v]], [[6e7u]], [[6e7t]], [[6e7s]], [[6e7r]] – XlNMDAR2B (mutant) + NMDAR1 (mutant) + inhibitor<br />
**[[5ipu]], [[6e7x]], [[6e7w]], [[6e7v]], [[6e7u]], [[6e7t]], [[6e7s]], [[6e7r]] – XlNMDAR2B (mutant) + NMDAR1 (mutant) + inhibitor<br />
**[[3qel]], [[3qem]], [[5ewj]] – XlNMDAR ATD (mutant) + ifenprodil<br />
**[[3qel]], [[3qem]], [[5ewj]] – XlNMDAR ATD (mutant) + ifenprodil<br />
 +
 +
*''NMDAR subunit NR1B+NR2B''
 +
 +
**[[6wi1]] – rNMDAR – Cryo EM <br />
 +
**[[6whw]], [[6whx]], [[6why]] – rNMDAR + antagonist – Cryo EM <br />
*NMDAR subunit NR1+NR2A+NR2B
*NMDAR subunit NR1+NR2A+NR2B

Revision as of 08:27, 5 August 2020

3D structures of glutamate receptor

Updated on 05-August-2020

A topic page describing in detail the GluA2 structure described in 3kg2

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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