Spike protein

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*[[SARS-CoV-2 protein S]]
*[[SARS-CoV-2 protein S]]
*[[SARS-CoV-2 protein S priming by furin]] where the priming step induced by furin cleavage is '''animated'''.
*[[SARS-CoV-2 protein S priming by furin]] where the priming step induced by furin cleavage is '''animated'''.
 +
*[[SARS-CoV-2 spike protein fusion transformation]] with an '''animation''' and explanation of the membrane fusion mechanism.
*[[Coronavirus Disease 2019 (COVID-19)]]
*[[Coronavirus Disease 2019 (COVID-19)]]
*[[User:Andre Wu Le Chun/Sandbox 1|Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up]] about [[6vsb]]
*[[User:Andre Wu Le Chun/Sandbox 1|Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up]] about [[6vsb]]

Revision as of 19:51, 9 August 2020

Human coronavirus NL63 spike glycoprotein (magenta) complex with its ligand ACE2 (green) (PDB code 3kbh)

Drag the structure with the mouse to rotate

See Also

3D Structures of spike protein

Updated on 09-August-2020

References

  1. Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh CL, Abiona O, Graham BS, McLellan JS. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science. 2020 Feb 19. pii: science.abb2507. doi: 10.1126/science.abb2507. PMID:32075877 doi:http://dx.doi.org/10.1126/science.abb2507
  2. Tian X, Li C, Huang A, Xia S, Lu S, Shi Z, Lu L, Jiang S, Yang Z, Wu Y, Ying T. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody. Emerg Microbes Infect. 2020 Feb 17;9(1):382-385. doi:, 10.1080/22221751.2020.1729069. eCollection 2020. PMID:32065055 doi:http://dx.doi.org/10.1080/22221751.2020.1729069
  3. Wu K, Li W, Peng G, Li F. Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19970-4. Epub 2009 Nov 9. PMID:19901337

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