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6v7i
From Proteopedia
(Difference between revisions)
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==Structure of KPC-2 bound to Vaborbactam at 1.25 A== | ==Structure of KPC-2 bound to Vaborbactam at 1.25 A== | ||
| - | <StructureSection load='6v7i' size='340' side='right'caption='[[6v7i]]' scene=''> | + | <StructureSection load='6v7i' size='340' side='right'caption='[[6v7i]], [[Resolution|resolution]] 1.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V7I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V7I FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6v7i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V7I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V7I FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v7i OCA], [http://pdbe.org/6v7i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v7i RCSB], [http://www.ebi.ac.uk/pdbsum/6v7i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v7i ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4D6:{(3R,6S)-2-HYDROXY-3-[(THIOPHEN-2-YLACETYL)AMINO]-1,2-OXABORINAN-6-YL}ACETIC+ACID'>4D6</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla, kpc, kpc1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v7i OCA], [http://pdbe.org/6v7i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v7i RCSB], [http://www.ebi.ac.uk/pdbsum/6v7i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v7i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN]] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Beta-lactamase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chen Y]] | + | [[Category: Chen, Y]] |
| - | [[Category: Pemberton | + | [[Category: Pemberton, O A]] |
| + | [[Category: Boronate]] | ||
| + | [[Category: Carbapenemase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Inhibitor]] | ||
Revision as of 06:35, 19 August 2020
Structure of KPC-2 bound to Vaborbactam at 1.25 A
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