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5maj

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==CATHEPSIN L IN COMPLEX WITH 4-[cyclopentyl(imidazo[1,2-a]pyridin-2-ylmethyl)amino]-6-morpholino-1,3,5-triazine-2-carbonitrile==
==CATHEPSIN L IN COMPLEX WITH 4-[cyclopentyl(imidazo[1,2-a]pyridin-2-ylmethyl)amino]-6-morpholino-1,3,5-triazine-2-carbonitrile==
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<StructureSection load='5maj' size='340' side='right' caption='[[5maj]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
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<StructureSection load='5maj' size='340' side='right'caption='[[5maj]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5maj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MAJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MAJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5maj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MAJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MAJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7KH:~{N}-CYCLOPENTYL-~{N}-(IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL)-4-(IMINOMETHYL)-6-MORPHOLIN-4-YL-1,3,5-TRIAZIN-2-AMINE'>7KH</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7KH:~{N}-CYCLOPENTYL-~{N}-(IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL)-4-(IMINOMETHYL)-6-MORPHOLIN-4-YL-1,3,5-TRIAZIN-2-AMINE'>7KH</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mae|5mae]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mae|5mae]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSL, CTSL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5maj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5maj OCA], [http://pdbe.org/5maj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5maj RCSB], [http://www.ebi.ac.uk/pdbsum/5maj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5maj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5maj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5maj OCA], [http://pdbe.org/5maj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5maj RCSB], [http://www.ebi.ac.uk/pdbsum/5maj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5maj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
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*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
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*[[Cathepsin 3D structures|Cathepsin 3D structures]]
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*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Cathepsin L]]
[[Category: Cathepsin L]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Benz, J]]
[[Category: Benz, J]]
[[Category: Kuglstatter, A]]
[[Category: Kuglstatter, A]]

Revision as of 07:13, 19 August 2020

CATHEPSIN L IN COMPLEX WITH 4-[cyclopentyl(imidazo[1,2-a]pyridin-2-ylmethyl)amino]-6-morpholino-1,3,5-triazine-2-carbonitrile

PDB ID 5maj

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