5mju

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==Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101==
==Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101==
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<StructureSection load='5mju' size='340' side='right' caption='[[5mju]], [[Resolution|resolution]] 3.71&Aring;' scene=''>
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<StructureSection load='5mju' size='340' side='right'caption='[[5mju]], [[Resolution|resolution]] 3.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mju]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MJU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mju]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MJU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MJU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6Z6:2-AMINO-5,6,7,8-TETRAHYDRO-4-(4-METHOXYPHENYL)-7-(NAPHTHALEN-1-YL)-5-OXO-4H-CHROMENE-3-CARBONITRILE'>6Z6</scene>, <scene name='pdbligand=7O9:(2~{S},3~{S})-2-AZANYL-3-[[3-[[4-(TRIFLUOROMETHYL)PHENYL]CARBONYLAMINO]PHENYL]METHOXY]BUTANEDIOIC+ACID'>7O9</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6Z6:2-AMINO-5,6,7,8-TETRAHYDRO-4-(4-METHOXYPHENYL)-7-(NAPHTHALEN-1-YL)-5-OXO-4H-CHROMENE-3-CARBONITRILE'>6Z6</scene>, <scene name='pdbligand=7O9:(2~{S},3~{S})-2-AZANYL-3-[[3-[[4-(TRIFLUOROMETHYL)PHENYL]CARBONYLAMINO]PHENYL]METHOXY]BUTANEDIOIC+ACID'>7O9</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mju OCA], [http://pdbe.org/5mju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mju RCSB], [http://www.ebi.ac.uk/pdbsum/5mju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mju ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SLC1A3, EAAT1, GLAST, GLAST1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mju OCA], [http://pdbe.org/5mju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mju RCSB], [http://www.ebi.ac.uk/pdbsum/5mju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mju ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Assal, R]]
[[Category: Assal, R]]
[[Category: Canul-Tec, J]]
[[Category: Canul-Tec, J]]

Revision as of 07:21, 19 August 2020

Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101

PDB ID 5mju

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