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Insulin-like growth factor

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*IGF I
+
*IGF I residues 49-118
-
**[[2gf1]], [[3gf1]], [[1b9g]], [[1bqt]] – hIGF I – human – NMR<BR />
+
**[[2gf1]], [[3gf1]], [[1b9g]], [[1bqt]], [[6rva]] – hIGF I – human – NMR<BR />
**[[3lri]] - hIGF I (mutant) – NMR<BR />
**[[3lri]] - hIGF I (mutant) – NMR<BR />
-
**[[1tgr]] - hIGF I (mutant) <BR />
 
**[[1imx]], [[1gzr]], [[1gzy]], [[1gzz]], [[1h02]] - hIGF I<BR />
**[[1imx]], [[1gzr]], [[1gzy]], [[1gzz]], [[1h02]] - hIGF I<BR />
 +
**[[1tgr]] - hIGF I (mutant) <BR />
**[[1pmx]] – hIGF I + peptide - NMR<BR />
**[[1pmx]] – hIGF I + peptide - NMR<BR />
**[[1h59]] – hIGF I + IGF binding protein 5<BR />
**[[1h59]] – hIGF I + IGF binding protein 5<BR />
Line 27: Line 27:
**[[2dsq]] - hIGF I + IGF binding protein 4 + IGF binding protein 1<br />
**[[2dsq]] - hIGF I + IGF binding protein 4 + IGF binding protein 1<br />
**[[4xss]] - hIGF I + insulin receptor + insulin-like growth factor receptor peptide<br />
**[[4xss]] - hIGF I + insulin receptor + insulin-like growth factor receptor peptide<br />
 +
**[[5u8q]] - hIGF I + IGFI receptor + antibody<br />
 +
**[[6ff3]] - hIGF I + neural ectodermal development factor<br />
 +
**[[6pyh]] - hIGF I + mIGFI receptor – Cryo EM<br />
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*IGF II
+
*IGF II residues 25-91
**[[1igl]], [[5l3l]], [[5l3m]], [[5l3n]] - hIGF II – NMR<BR />
**[[1igl]], [[5l3l]], [[5l3m]], [[5l3n]] - hIGF II – NMR<BR />
**[[3e4z]] – hIGF II + insulin-degrading enzyme<BR />
**[[3e4z]] – hIGF II + insulin-degrading enzyme<BR />
-
**[[3rk3]] – hIGF II + antibody
+
**[[6um2]] - hIGF II + bIGFII receptor Cryo EM<br />
 +
**[[6vwg]], [[6vwi]] - hIGF II + IGFI receptor – Cryo EM<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:29, 24 August 2020

Structure of insulin-like growth factor I complex with detergent (PDB entry 1gzr)

Drag the structure with the mouse to rotate

3D structures of insulin-like growth factor

Updated on 24-August-2020

References

  1. Wood AW, Duan C, Bern HA. Insulin-like growth factor signaling in fish. Int Rev Cytol. 2005;243:215-85. PMID:15797461 doi:http://dx.doi.org/10.1016/S0074-7696(05)43004-1
  2. Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr. 2001 Nov;131(11 Suppl):3109S-20S. PMID:11694656
  3. Mohamed-Ali V, Pinkney J. Therapeutic potential of insulin-like growth factor-1 in patients with diabetes mellitus. Treat Endocrinol. 2002;1(6):399-410. PMID:15832492

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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