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5nma

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==Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain==
==Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain==
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<StructureSection load='5nma' size='340' side='right' caption='[[5nma]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='5nma' size='340' side='right'caption='[[5nma]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5nma]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NMA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5nma]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NMA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NMA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9CW:(1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{S},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol'>9CW</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9CW:(1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{S},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol'>9CW</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vdra, nr1i1a, vdr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nma OCA], [http://pdbe.org/5nma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nma RCSB], [http://www.ebi.ac.uk/pdbsum/5nma PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nma ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5nma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nma OCA], [http://pdbe.org/5nma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nma RCSB], [http://www.ebi.ac.uk/pdbsum/5nma PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nma ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5nma" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5nma" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Vitamin D receptor 3D structures|Vitamin D receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brachidanio rerio]]
[[Category: Histone acetyltransferase]]
[[Category: Histone acetyltransferase]]
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[[Category: Large Structures]]
[[Category: Belorusova, A Y]]
[[Category: Belorusova, A Y]]
[[Category: Rochel, N]]
[[Category: Rochel, N]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Vitamin d nuclear receptor]]
[[Category: Vitamin d nuclear receptor]]

Revision as of 12:08, 26 August 2020

Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain

PDB ID 5nma

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