1npa
From Proteopedia
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(New page: 200px<br /> <applet load="1npa" size="450" color="white" frame="true" align="right" spinBox="true" caption="1npa, resolution 2.Å" /> '''crystal structure of ...)
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Revision as of 12:16, 8 November 2007
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crystal structure of HIV-1 protease-hup
About this Structure
1NPA is a Single protein structure of sequence from Human immunodeficiency virus 1 with 3NH as ligand. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
Reference
An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex., Smith AB 3rd, Hirschmann R, Pasternak A, Yao W, Sprengeler PA, Holloway MK, Kuo LC, Chen Z, Darke PL, Schleif WA, J Med Chem. 1997 Aug 1;40(16):2440-4. PMID:9258349
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