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From Proteopedia
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== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/EMC5_YEAST EMC5_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC2_YEAST EMC2_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC6_YEAST EMC6_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC1_YEAST EMC1_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/SOP4_YEAST SOP4_YEAST]] Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.<ref>PMID:12230471</ref> <ref>PMID:9265642</ref> [[http://www.uniprot.org/uniprot/EMC10_YEAST EMC10_YEAST]] Non essential component of the endoplasmic reticulum (ER) membrane protein complex (EMC) involved in ER-associated degradation (ERAD) and proper assembly of multi-pass transmembrane proteins (Probable). EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein TOM5 of TOM (translocase of the mitochondrial outer membrane) complex (Probable).<ref>PMID:26512320</ref> | + | [[http://www.uniprot.org/uniprot/EMC5_YEAST EMC5_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC2_YEAST EMC2_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC6_YEAST EMC6_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC1_YEAST EMC1_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/SOP4_YEAST SOP4_YEAST]] Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.<ref>PMID:12230471</ref> <ref>PMID:9265642</ref> [[http://www.uniprot.org/uniprot/EMC3_YEAST EMC3_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). [[http://www.uniprot.org/uniprot/EMC10_YEAST EMC10_YEAST]] Non essential component of the endoplasmic reticulum (ER) membrane protein complex (EMC) involved in ER-associated degradation (ERAD) and proper assembly of multi-pass transmembrane proteins (Probable). EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein TOM5 of TOM (translocase of the mitochondrial outer membrane) complex (Probable).<ref>PMID:26512320</ref> [[http://www.uniprot.org/uniprot/EMC4_YEAST EMC4_YEAST]] The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). |
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 07:09, 2 September 2020
Structure of the S. cerevisiae ER membrane complex
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