Mandelate racemase
From Proteopedia
(Difference between revisions)
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**[[1mns]], [[1mdr]] – PpMAR + α-phenyl lactate <br /> | **[[1mns]], [[1mdr]] – PpMAR + α-phenyl lactate <br /> | ||
| - | **[[3ops]] – GeMAR + lactate<br /> | ||
**[[1mra]], [[1dtn]] – PpMAR (mutant) + atrolactate<br /> | **[[1mra]], [[1dtn]] – PpMAR (mutant) + atrolactate<br /> | ||
**[[1mdl]] - PpMAR (mutant) + mandelate<br /> | **[[1mdl]] - PpMAR (mutant) + mandelate<br /> | ||
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**[[4fp1]] – PpMAR + inhibitor<br /> | **[[4fp1]] – PpMAR + inhibitor<br /> | ||
**[[4x2p]] – PpMAR + 3-hydroxypyruvate<br /> | **[[4x2p]] – PpMAR + 3-hydroxypyruvate<br /> | ||
| - | **[[ | + | **[[6vim]] – PpMAR + boronic acid derivative<br /> |
**[[3uxk]], [[3uxl]] – PpMAR + intermediate analog<br /> | **[[3uxk]], [[3uxl]] – PpMAR + intermediate analog<br /> | ||
**[[3sbf]] – VbMAR (mutant) + arabinonate <br /> | **[[3sbf]] – VbMAR (mutant) + arabinonate <br /> | ||
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**[[4gfi]] – AtMAR + dipeptide epimerase<br /> | **[[4gfi]] – AtMAR + dipeptide epimerase<br /> | ||
**[[4h19]] – AtMAR + ribonohydroxamate<br /> | **[[4h19]] – AtMAR + ribonohydroxamate<br /> | ||
| + | **[[3ops]] – GeMAR + lactate<br /> | ||
| + | **[[3tte]] - BrMAR + mandelate<br /> | ||
}} | }} | ||
== References == | == References == | ||
Revision as of 08:58, 3 September 2020
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3D structures of mandelate racemase
Updated on 03-September-2020
References
- ↑ Powers VM, Koo CW, Kenyon GL, Gerlt JA, Kozarich JW. Mechanism of the reaction catalyzed by mandelate racemase. 1. Chemical and kinetic evidence for a two-base mechanism. Biochemistry. 1991 Sep 24;30(38):9255-63. PMID:1892833
- ↑ Landro JA, Gerlt JA, Kozarich JW, Koo CW, Shah VJ, Kenyon GL, Neidhart DJ, Fujita S, Petsko GA. The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate. Biochemistry. 1994 Jan 25;33(3):635-43. PMID:8292591
