6wue
From Proteopedia
(Difference between revisions)
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==Tetragonal crystal form of SbtB from Synechocystis PCC6803== | ==Tetragonal crystal form of SbtB from Synechocystis PCC6803== | ||
| - | <StructureSection load='6wue' size='340' side='right'caption='[[6wue]]' scene=''> | + | <StructureSection load='6wue' size='340' side='right'caption='[[6wue]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WUE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WUE FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6wue]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WUE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WUE FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wue OCA], [http://pdbe.org/6wue PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wue RCSB], [http://www.ebi.ac.uk/pdbsum/6wue PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wue ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">slr1513 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1148 Aphanocapsa sp. (strain N-1)])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wue OCA], [http://pdbe.org/6wue PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wue RCSB], [http://www.ebi.ac.uk/pdbsum/6wue PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wue ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The PII-like protein SbtB has been identified as a regulator of SbtA, which is one of the key bicarbonate transporters in cyanobacteria. While SbtB from Synechocystis sp. PCC 6803 has previously been shown to be a trimer, a new crystal form is reported here which crystallizes in what is thought to be a non-native tetramer in the crystal, with the C-terminus in an extended conformation. The crystal structure shows the formation of an intermolecular disulfide bond at Cys94 between SbtB monomers, which may stabilize this conformation in the crystal. This motivates the need for future studies to investigate the potential role that the oxidation and reduction of these cysteines may play in the activation and/or function of SbtB. | ||
| + | |||
| + | Tetragonal crystal form of the cyanobacterial bicarbonate-transporter regulator SbtB from Synechocystis sp. PCC 6803.,Bu G, Simmons CR, Nielsen DR, Nannenga BL Acta Crystallogr F Struct Biol Commun. 2020 Sep 1;76(Pt 9):438-443. doi:, 10.1107/S2053230X20010523. Epub 2020 Aug 19. PMID:32880592<ref>PMID:32880592</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6wue" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bu G]] | + | [[Category: Bu, G]] |
| - | [[Category: Nannenga | + | [[Category: Nannenga, B L]] |
| - | [[Category: Nielsen | + | [[Category: Nielsen, D R]] |
| - | [[Category: Simmons | + | [[Category: Simmons, C R]] |
| + | [[Category: Regulator of cyanobacterial bicarbonate transporter]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 10:17, 16 September 2020
Tetragonal crystal form of SbtB from Synechocystis PCC6803
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