Pertussis toxin
From Proteopedia
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<StructureSection load='1prt' size='350' side='right' caption='Pertussis toxin (PDB entry [[1prt]])' scene=''> | <StructureSection load='1prt' size='350' side='right' caption='Pertussis toxin (PDB entry [[1prt]])' scene=''> | ||
== Function == | == Function == | ||
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[[1prt]] – BpPT - ''Bordetella pertussis''<br /> | [[1prt]] – BpPT - ''Bordetella pertussis''<br /> | ||
[[1pto]] – BpPT + galactose<br /> | [[1pto]] – BpPT + galactose<br /> | ||
| - | [[1bcp]] – BpPT + ATP | + | [[1bcp]] – BpPT + ATP<br /> |
| + | [[6ro0]] – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4<br /> | ||
'''Pertactin''' | '''Pertactin''' | ||
Revision as of 08:17, 21 September 2020
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3D Structures of Pertussis toxin
1prt – BpPT - Bordetella pertussis
1pto – BpPT + galactose
1bcp – BpPT + ATP
6ro0 – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4
Pertactin
1dab - BpPer
2iou - Per extracellular domain + major tropism determinant - Bordetella bronchiseptica
References
- ↑ Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005
- ↑ Connelly CE, Sun Y, Carbonetti NH. Pertussis toxin exacerbates and prolongs airway inflammatory responses during Bordetella pertussis infection. Infect Immun. 2012 Dec;80(12):4317-32. doi: 10.1128/IAI.00808-12. Epub 2012 Oct, 1. PMID:23027529 doi:http://dx.doi.org/10.1128/IAI.00808-12
