3i9j
From Proteopedia
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==Crystal structure of ADP ribosyl cyclase complexed with a substrate analog and a product nicotinamide== | ==Crystal structure of ADP ribosyl cyclase complexed with a substrate analog and a product nicotinamide== | ||
- | <StructureSection load='3i9j' size='340' side='right' caption='[[3i9j]], [[Resolution|resolution]] 2.18Å' scene=''> | + | <StructureSection load='3i9j' size='340' side='right'caption='[[3i9j]], [[Resolution|resolution]] 2.18Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3i9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I9J OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[3i9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I9J OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3I9J FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AVV:[(2R,3S,4R,5R)-5-(6-AMINO-2-FLUORO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+[(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>AVV</scene>, <scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene>, <scene name='pdbligand=NFD:NICOTINAMIDE+2-FLUORO-ADENINE+DINUCLEOTIDE'>NFD</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AVV:[(2R,3S,4R,5R)-5-(6-AMINO-2-FLUORO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+[(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+DIHYDROGEN+DIPHOSPHATE'>AVV</scene>, <scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene>, <scene name='pdbligand=NFD:NICOTINAMIDE+2-FLUORO-ADENINE+DINUCLEOTIDE'>NFD</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i9k|3i9k]], [[3i9l|3i9l]], [[3i9m|3i9m]], [[3i9n|3i9n]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i9k|3i9k]], [[3i9l|3i9l]], [[3i9m|3i9m]], [[3i9n|3i9n]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3i9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i9j OCA], [http://pdbe.org/3i9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i9j RCSB], [http://www.ebi.ac.uk/pdbsum/3i9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i9j ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aplca]] | [[Category: Aplca]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Graeff, R]] | [[Category: Graeff, R]] | ||
[[Category: Hao, Q]] | [[Category: Hao, Q]] |
Revision as of 11:53, 23 September 2020
Crystal structure of ADP ribosyl cyclase complexed with a substrate analog and a product nicotinamide
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Categories: Aplca | Large Structures | Graeff, R | Hao, Q | Jiang, H | Kriksunov, I A | Lee, H C | Lin, H | Liu, Q | Oppenheimer, N | Potter, B V.L | Zhang, B | Adp-ribosyl cyclase | Disulfide bond | Enzyme-analog-nicotinamide complex | Fertilization | Homodimer | Hydrolase | Nad