5tzy

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==GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666==
==GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666==
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<StructureSection load='5tzy' size='340' side='right' caption='[[5tzy]], [[Resolution|resolution]] 3.22&Aring;' scene=''>
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<StructureSection load='5tzy' size='340' side='right'caption='[[5tzy]], [[Resolution|resolution]] 3.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tzy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TZY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tzy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TZY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5TZY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7OS:(2S,3R)-3-cyclopropyl-3-[(2R)-2-(1-{(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl}piperidin-4-yl)-3,4-dihydro-2H-1-benzopyran-7-yl]-2-methylpropanoic+acid'>7OS</scene>, <scene name='pdbligand=MK6:(5aR,6S,6aS)-3-({2,6-dimethyl-4-[3-(methylsulfonyl)propoxy][1,1-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic+acid'>MK6</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7OS:(2S,3R)-3-cyclopropyl-3-[(2R)-2-(1-{(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl}piperidin-4-yl)-3,4-dihydro-2H-1-benzopyran-7-yl]-2-methylpropanoic+acid'>7OS</scene>, <scene name='pdbligand=MK6:(5aR,6S,6aS)-3-({2,6-dimethyl-4-[3-(methylsulfonyl)propoxy][1,1-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic+acid'>MK6</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tzr|5tzr]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tzr|5tzr]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tzy OCA], [http://pdbe.org/5tzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tzy RCSB], [http://www.ebi.ac.uk/pdbsum/5tzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tzy ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5tzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tzy OCA], [http://pdbe.org/5tzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tzy RCSB], [http://www.ebi.ac.uk/pdbsum/5tzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tzy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
[[Category: Byrne, N]]
[[Category: Byrne, N]]

Revision as of 12:23, 23 September 2020

GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666

PDB ID 5tzy

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