This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5u28

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==BRD4 first bromodomain (BD1) in complex with dual PI3 kinase inhibitor SF2523==
==BRD4 first bromodomain (BD1) in complex with dual PI3 kinase inhibitor SF2523==
-
<StructureSection load='5u28' size='340' side='right' caption='[[5u28]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+
<StructureSection load='5u28' size='340' side='right'caption='[[5u28]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5u28]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U28 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5u28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U28 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5U28 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=82V:3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-5-(MORPHOLIN-4-YL)-7H-THIENO[3,2-B]PYRAN-7-ONE'>82V</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=82V:3-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-5-(MORPHOLIN-4-YL)-7H-THIENO[3,2-B]PYRAN-7-ONE'>82V</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u2f|5u2f]], [[5u2c|5u2c]], [[5u2e|5u2e]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u2f|5u2f]], [[5u2c|5u2c]], [[5u2e|5u2e]]</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u28 OCA], [http://pdbe.org/5u28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u28 RCSB], [http://www.ebi.ac.uk/pdbsum/5u28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u28 ProSAT]</span></td></tr>
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5u28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u28 OCA], [http://pdbe.org/5u28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u28 RCSB], [http://www.ebi.ac.uk/pdbsum/5u28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u28 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
Line 21: Line 22:
</div>
</div>
<div class="pdbe-citations 5u28" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5u28" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Human]]
 +
[[Category: Large Structures]]
[[Category: Andrews, F H]]
[[Category: Andrews, F H]]
[[Category: Kutateladze, T G]]
[[Category: Kutateladze, T G]]

Revision as of 12:24, 23 September 2020

BRD4 first bromodomain (BD1) in complex with dual PI3 kinase inhibitor SF2523

PDB ID 5u28

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools