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5uj2

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==Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU==
==Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU==
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<StructureSection load='5uj2' size='340' side='right' caption='[[5uj2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='5uj2' size='340' side='right'caption='[[5uj2]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5uj2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UJ2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5uj2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UJ2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8B4:(1S)-1-(4-AMINOIMIDAZO[2,1-F][1,2,4]TRIAZIN-7-YL)-1,4-ANHYDRO-2-DEOXY-2-FLUORO-5-O-[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]-2-METHYL-D-RIBITOL'>8B4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8B4:(1S)-1-(4-AMINOIMIDAZO[2,1-F][1,2,4]TRIAZIN-7-YL)-1,4-ANHYDRO-2-DEOXY-2-FLUORO-5-O-[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]-2-METHYL-D-RIBITOL'>8B4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wtg|4wtg]], [[4wtd|4wtd]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wtg|4wtg]], [[4wtd|4wtd]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uj2 OCA], [http://pdbe.org/5uj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5uj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uj2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5uj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uj2 OCA], [http://pdbe.org/5uj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uj2 RCSB], [http://www.ebi.ac.uk/pdbsum/5uj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uj2 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Appleby, T C]]
[[Category: Appleby, T C]]
[[Category: Edwards, T E]]
[[Category: Edwards, T E]]

Revision as of 12:38, 23 September 2020

Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations and Delta8 neta hairpoin loop deletion in complex with GS-639476 (diphsohate version of GS-9813), Mn2+ and symmetrical primer template 5'-AUAAAUUU

PDB ID 5uj2

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