5uwf

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==Crystal structure of human PDE10A in complex with inhibitor 16d==
==Crystal structure of human PDE10A in complex with inhibitor 16d==
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<StructureSection load='5uwf' size='340' side='right' caption='[[5uwf]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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<StructureSection load='5uwf' size='340' side='right'caption='[[5uwf]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5uwf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UWF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5uwf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UWF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UWF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8Q7:9-[(1S)-2,2-DIFLUOROCYCLOPROPANE-1-CARBONYL]-6-[(4-METHOXYPHENYL)METHYL]-8,9,10,11-TETRAHYDROPYRIDO[4,3 4,5]THIENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5(6H)-ONE'>8Q7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8Q7:9-[(1S)-2,2-DIFLUOROCYCLOPROPANE-1-CARBONYL]-6-[(4-METHOXYPHENYL)METHYL]-8,9,10,11-TETRAHYDROPYRIDO[4,3 4,5]THIENO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5(6H)-ONE'>8Q7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uwf OCA], [http://pdbe.org/5uwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uwf RCSB], [http://www.ebi.ac.uk/pdbsum/5uwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uwf ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE10A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5uwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uwf OCA], [http://pdbe.org/5uwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uwf RCSB], [http://www.ebi.ac.uk/pdbsum/5uwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uwf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5uwf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5uwf" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Aertgeerts, K]]
[[Category: Aertgeerts, K]]
[[Category: Barker, R]]
[[Category: Barker, R]]

Revision as of 08:25, 30 September 2020

Crystal structure of human PDE10A in complex with inhibitor 16d

PDB ID 5uwf

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