5uy8

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==Crystal structure of AICARFT bound to an antifolate==
==Crystal structure of AICARFT bound to an antifolate==
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<StructureSection load='5uy8' size='340' side='right' caption='[[5uy8]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
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<StructureSection load='5uy8' size='340' side='right'caption='[[5uy8]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5uy8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UY8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UY8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5uy8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UY8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UY8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8UM:5-[(5S)-5-ethyl-5-methyl-6-oxo-1,4,5,6-tetrahydropyridin-3-yl]-N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)thiophene-2-sulfonamide'>8UM</scene>, <scene name='pdbligand=AMZ:AMINOIMIDAZOLE+4-CARBOXAMIDE+RIBONUCLEOTIDE'>AMZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8UM:5-[(5S)-5-ethyl-5-methyl-6-oxo-1,4,5,6-tetrahydropyridin-3-yl]-N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)thiophene-2-sulfonamide'>8UM</scene>, <scene name='pdbligand=AMZ:AMINOIMIDAZOLE+4-CARBOXAMIDE+RIBONUCLEOTIDE'>AMZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uz0|5uz0]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uz0|5uz0]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uy8 OCA], [http://pdbe.org/5uy8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uy8 RCSB], [http://www.ebi.ac.uk/pdbsum/5uy8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uy8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5uy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uy8 OCA], [http://pdbe.org/5uy8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uy8 RCSB], [http://www.ebi.ac.uk/pdbsum/5uy8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uy8 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5uy8" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5uy8" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bifunctional purine biosynthesis protein PURH|Bifunctional purine biosynthesis protein PURH]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Atwell, S]]
[[Category: Atwell, S]]
[[Category: Clawson, D]]
[[Category: Clawson, D]]

Revision as of 08:27, 30 September 2020

Crystal structure of AICARFT bound to an antifolate

PDB ID 5uy8

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