5v54
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of 5-HT1B receptor in complex with methiothepin== | ==Crystal structure of 5-HT1B receptor in complex with methiothepin== | ||
| - | <StructureSection load='5v54' size='340' side='right' caption='[[5v54]], [[Resolution|resolution]] 3.90Å' scene=''> | + | <StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution|resolution]] 3.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5v54]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [http://pdbe.org/5v54 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [http://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | [[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Caffrey, M]] | [[Category: Caffrey, M]] | ||
[[Category: Cai, X]] | [[Category: Cai, X]] | ||
Revision as of 08:31, 30 September 2020
Crystal structure of 5-HT1B receptor in complex with methiothepin
| |||||||||||
Categories: Large Structures | Caffrey, M | Cai, X | Dai, A | Huang, C Y | Jiang, Y | Liu, B | Liu, P | Melcher, K | Waal, P de | Wang, M T | Wang, M W | Xu, H E | Xu, Y | Yang, D | Yin, W C | Yin, Y | Zhou, X E | 5-hydroxytryptamine | Electron transport | Gpcr antagonist | Ob1
