This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6st7
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp== | ==Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp== | ||
| - | <StructureSection load='6st7' size='340' side='right'caption='[[6st7]]' scene=''> | + | <StructureSection load='6st7' size='340' side='right'caption='[[6st7]], [[Resolution|resolution]] 2.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ST7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ST7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6st7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ST7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ST7 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6st7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6st7 OCA], [http://pdbe.org/6st7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6st7 RCSB], [http://www.ebi.ac.uk/pdbsum/6st7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6st7 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mi7|1mi7]], [[1jhg|1jhg]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpR, rtrY, b4393, JW4356 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6st7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6st7 OCA], [http://pdbe.org/6st7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6st7 RCSB], [http://www.ebi.ac.uk/pdbsum/6st7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6st7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRPR_ECOLI TRPR_ECOLI]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ecoli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Carey J]] | + | [[Category: Carey, J]] |
| - | [[Category: Drouard F]] | + | [[Category: Drouard, F]] |
| - | [[Category: Lawson | + | [[Category: Lawson, C L]] |
| - | [[Category: | + | [[Category: Leggio, L Lo]] |
| - | [[Category: | + | [[Category: Linse, S]] |
| - | [[Category: Schulz A]] | + | [[Category: Schulz, A]] |
| - | [[Category: Sprenger J]] | + | [[Category: Sprenger, J]] |
| - | [[Category: | + | [[Category: Wachenfeldt, C von]] |
| + | [[Category: Dna binding protein]] | ||
| + | [[Category: Domain swapping]] | ||
| + | [[Category: Hostal]] | ||
| + | [[Category: L-trp binding]] | ||
Revision as of 06:36, 7 October 2020
Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp
| |||||||||||
