5wxs
From Proteopedia
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| ==Crystal structure of uPA in complex with S2444== | ==Crystal structure of uPA in complex with S2444== | ||
| - | <StructureSection load='5wxs' size='340' side='right' caption='[[5wxs]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='5wxs' size='340' side='right'caption='[[5wxs]], [[Resolution|resolution]] 2.30Å' scene=''> | 
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5wxs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WXS OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5wxs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WXS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5WXS FirstGlance]. <br> | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7YF:(2R)-N-[2-[[(2S)-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-1,2-dihydropyrrole-2-carboxamide'>7YF</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7YF:(2R)-N-[2-[[(2S)-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-1,2-dihydropyrrole-2-carboxamide'>7YF</scene></td></tr> | 
| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wxf|5wxf]], [[5wxo|5wxo]], [[5wxp|5wxp]], [[5wxq|5wxq]], [[5wxr|5wxr]], [[5wxt|5wxt]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wxf|5wxf]], [[5wxo|5wxo]], [[5wxp|5wxp]], [[5wxq|5wxq]], [[5wxr|5wxr]], [[5wxt|5wxt]]</td></tr> | ||
| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/U-plasminogen_activator U-plasminogen activator], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.73 3.4.21.73] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/U-plasminogen_activator U-plasminogen activator], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.73 3.4.21.73] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5wxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wxs OCA], [http://pdbe.org/5wxs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wxs RCSB], [http://www.ebi.ac.uk/pdbsum/5wxs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wxs ProSAT]</span></td></tr> | 
| </table> | </table> | ||
| == Disease == | == Disease == | ||
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| == Function == | == Function == | ||
| [[http://www.uniprot.org/uniprot/UROK_HUMAN UROK_HUMAN]] Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.  | [[http://www.uniprot.org/uniprot/UROK_HUMAN UROK_HUMAN]] Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.  | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Urokinase 3D Structures|Urokinase 3D Structures]] | ||
| == References == | == References == | ||
| <references/> | <references/> | ||
| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| [[Category: U-plasminogen activator]] | [[Category: U-plasminogen activator]] | ||
| [[Category: Huang, M]] | [[Category: Huang, M]] | ||
Revision as of 07:19, 7 October 2020
Crystal structure of uPA in complex with S2444
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