1csn

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[[Image:1csn.gif|left|200px]]
[[Image:1csn.gif|left|200px]]
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{{Structure
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|PDB= 1csn |SIZE=350|CAPTION= <scene name='initialview01'>1csn</scene>, resolution 2.0&Aring;
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The line below this paragraph, containing "STRUCTURE_1csn", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY=
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{{STRUCTURE_1csn| PDB=1csn | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1csn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1csn OCA], [http://www.ebi.ac.uk/pdbsum/1csn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1csn RCSB]</span>
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}}
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'''BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP'''
'''BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP'''
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[[Category: Cheng, X.]]
[[Category: Cheng, X.]]
[[Category: Xu, R M.]]
[[Category: Xu, R M.]]
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[[Category: phosphotransferase]]
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[[Category: Phosphotransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:04:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:27:48 2008''
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Revision as of 10:04, 2 May 2008

Image:1csn.gif

Template:STRUCTURE 1csn

BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP


Overview

The structure of a truncated variant of casein kinase-1 from Schizosaccharomyces pombe, has been determined in complex with MgATP at 2.0 A resolution. The model resembles the 'closed', ATP-bound conformations of the cyclin-dependent kinase 2 and the cAMP-dependent protein kinase, with clear differences in the structure of surface loops that impart unique features to casein kinase-1. The structure is of unphosphorylated, active conformation of casein kinase-1 and the peptide-binding site is fully accessible to substrate.

About this Structure

1CSN is a Single protein structure of sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

Crystal structure of casein kinase-1, a phosphate-directed protein kinase., Xu RM, Carmel G, Sweet RM, Kuret J, Cheng X, EMBO J. 1995 Mar 1;14(5):1015-23. PMID:7889932 Page seeded by OCA on Fri May 2 13:04:25 2008

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