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3t9c

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==Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and inositol hexakisphosphate (IP6)==
==Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and inositol hexakisphosphate (IP6)==
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<StructureSection load='3t9c' size='340' side='right' caption='[[3t9c]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='3t9c' size='340' side='right'caption='[[3t9c]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3t9c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T9C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3t9c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T9C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3T9C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t54|3t54]], [[3t7a|3t7a]], [[3t99|3t99]], [[3t9a|3t9a]], [[3t9b|3t9b]], [[3t9d|3t9d]], [[3t9e|3t9e]], [[3t9f|3t9f]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t54|3t54]], [[3t7a|3t7a]], [[3t99|3t99]], [[3t9a|3t9a]], [[3t9b|3t9b]], [[3t9d|3t9d]], [[3t9e|3t9e]], [[3t9f|3t9f]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIP5K2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIP5K2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diphosphoinositol-pentakisphosphate_kinase Diphosphoinositol-pentakisphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.24 2.7.4.24] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diphosphoinositol-pentakisphosphate_kinase Diphosphoinositol-pentakisphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.24 2.7.4.24] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t9c OCA], [http://pdbe.org/3t9c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t9c RCSB], [http://www.ebi.ac.uk/pdbsum/3t9c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t9c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3t9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t9c OCA], [http://pdbe.org/3t9c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t9c RCSB], [http://www.ebi.ac.uk/pdbsum/3t9c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t9c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[Category: Diphosphoinositol-pentakisphosphate kinase]]
[[Category: Diphosphoinositol-pentakisphosphate kinase]]
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Falck, J]]
[[Category: Falck, J]]
[[Category: Hall, T M.T]]
[[Category: Hall, T M.T]]

Revision as of 05:56, 14 October 2020

Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and inositol hexakisphosphate (IP6)

PDB ID 3t9c

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