Gliding protein

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(New page: <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> describing Jmol <ref>PMID:21638687</ref> to the rescue. == Function == '''Gliding p...)
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<StructureSection load='6izw' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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'''Gliding protein''' or '''Mutual gliding-motility protein''' or '''Gliding motility protein'''
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'''Gliding protein''' or '''Mutual gliding-motility protein''' or '''Gliding motility protein''' (MglA and MglB). '''MglA''' is related to GTPase and is required for the normal operation of adventurous and social motility and multicellular development of some bacteria<ref>PMID:20196075</ref>. In''Myxococcus xanthus'' MglA regulates the movement of the bacteria on surfaces. '''MglB''' is MglA cognate GTPase activating protein<ref>PMID:31110363</ref>.
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== Disease ==
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== Relevance ==
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== Structural highlights ==
== Structural highlights ==
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**[[3t12]] - TtMglA + MglB + GDP <br />
**[[3t12]] - TtMglA + MglB + GDP <br />
**[[3t1q]] - TtMglA + MglB + GNP<br />
**[[3t1q]] - TtMglA + MglB + GNP<br />
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**[[6izw]], [[5h5b]] - MxMglA + MglB + GSP<br />
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**[[6izw]] - MxMglA + MglB + GSP<br />
== References ==
== References ==
<references/>
<references/>

Revision as of 06:43, 17 October 2020

Caption for this structure

Drag the structure with the mouse to rotate

3D structures of gliding protein

  • MglA
  • MglB
  • MglA+MglB
    • 3t12 - TtMglA + MglB + GDP
    • 3t1q - TtMglA + MglB + GNP
    • 6izw - MxMglA + MglB + GSP

References

  1. Patryn J, Allen K, Dziewanowska K, Otto R, Hartzell PL. Localization of MglA, an essential gliding motility protein in Myxococcus xanthus. Cytoskeleton (Hoboken). 2010 May;67(5):322-37. doi: 10.1002/cm.20447. PMID:20196075 doi:http://dx.doi.org/10.1002/cm.20447
  2. Szadkowski D, Harms A, Carreira LAM, Wigbers M, Potapova A, Wuichet K, Keilberg D, Gerland U, Sogaard-Andersen L. Spatial control of the GTPase MglA by localized RomR-RomX GEF and MglB GAP activities enables Myxococcus xanthus motility. Nat Microbiol. 2019 Aug;4(8):1344-1355. doi: 10.1038/s41564-019-0451-4. Epub 2019, May 20. PMID:31110363 doi:http://dx.doi.org/10.1038/s41564-019-0451-4

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