Ras-related protein Rab

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</StructureSection>
</StructureSection>
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==3D structures of Ras-related protein Rab==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Rab-1 GTPase domain 1-178
 
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**[[2fol]] – hRab-1 + GDP - human<br />
 
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**[[6sku]] – hRab-1 + AnkX + GDP<br />
 
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**[[5szh]], [[5szk]] – hRab-1 + Mical-cL + GNP<br />
 
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**[[4i1o]] – hRab-1 + LepB + GDP<br />
 
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**[[4fmb]] – hRab-1 + VirA + GDP<br />
 
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**[[3tkl]] – hRab-1 + LidA + GTP<br />
 
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**[[3sfv]] – hRab-1 (mutant) + LidA + GDP<br />
 
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**[[3nkv]] – hRab-1 + GNP + AMP<br />
 
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**[[3jza]], [[2wwx]], [[3l0i]] – hRab-1 + DrrA <br />
 
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**[[5o74]] – hRab-1 + DrrA + GDP <br />
 
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*Rab-2
 
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**[[2a5j]] – hRab-2 + GDP<br />
 
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*Rab-3
 
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**[[2gf9]] – hRab-3 + GDP <br />
 
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**[[3rab]] – Rab-3 + GNP - rat<br />
 
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**[[4rkf]] – DmRab-3 + GDP - ''Drosophila melanogaster''<br />
 
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*Rab-4
 
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**[[2o52]] – hRab-4 + GDP<br />
 
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**[[1yu9]] – hRab-4 + GNP<br />
 
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*Rab-5C
 
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**[[4kyi]] – hRab-5C + VipD + GNP<br />
 
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**[[1z02]] – mRab-5C (mutant) + GNP - mouse<br />
 
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**[[1z0d]], [[1z0a]] – mRab-5C + GDP <br />
 
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**[[1huq]] – mRab-5C + GNP <br />
 
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*Rab-6
 
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**[[2e9s]], [[2fe4]], [[4dkx]] – hRab-6 + GDP <br />
 
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**[[2ffq]] – hRab-6 + GSP <br />
 
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**[[2gil]] – hRab-6 + GTP <br />
 
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**[[1yzq]] – hRab-6 + GNP <br />
 
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**[[3bbp]] – hRab-6 + GCC185 + GTP <br />
 
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**[[3cwz]] – mRab-6 + R6IP1 + GTP <br />
 
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**[[5lef]] – mRab-6 + KIF20A + GTP <br />
 
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**[[2y8e]] – DmRab-5C + GNP <br />
 
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*Rab-7L1
 
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**[[6hh2]] – hRab-7L1 + GDP <br />
 
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*Rab-8
 
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**[[6sq2]] – hRab-8 + GTP<br />
 
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**[[6stg]], [[4lhw]] – hRab-8 + GNP<br />
 
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**[[6stf]], [[4lhv]] – hRab-8 + GDP<br />
 
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*Rab-9
 
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**[[1wms]] – hRab-9 + GDP<br />
 
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**[[2ocb]] – hRab-9 + GNP<br />
 
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**[[1s8f]] – Rab-9 + GDP - dog<br />
 
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**[[1yzl]] – mRab-9 + GNP<br />
 
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**[[4qxa]] – mRab-9 + RUTBC2 + GTP<br />
 
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*Rab-11A complex with nucleotide
 
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**[[1oiv]], [[6yi1]] – hRab-11A + GDP<br />
 
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**[[1oix]] – hRab-11A (mutant) + GDP <br />
 
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**[[5ez5]] – hRab-11A (mutant) + GTP <br />
 
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**[[1yzk]] – hRab-11A + GppNHp<br />
 
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**[[1oiw]] – hRab-11A (mutant) + GTPγS <br />
 
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**[[3bfk]] – Rab-11A + GDP – ''Plasmodium falciparum''<br />
 
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**[[5xr4]] – AtRab-11A + GDP – ''Arabidopsis thaliana''<br />
 
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**[[5xr7]] – AtRab-11A (mutant) + GTP <br />
 
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**[[5xr6]] – AtRab-11A + GppNHp<br />
 
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*Rab-11A other complexes
 
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**[[4c4p]] – hRab-11A + Rab11 family-interacting protein 2 <br />
 
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**[[2gzd]], [[2gzh]] – hRab-11A (mutant) + Rab11 family-interacting protein 2 <br />
 
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**[[2hv8]], [[2d7c]] – hRab-11A (mutant) + Rab11 family-interacting protein 3<br />
 
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**[[4d0m]] – hRab-11A (mutant) + Rab11 family-interacting protein 3 + PI4KB<br />
 
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**[[4uj5]] – hRab-11A (mutant) + Rab-3A interacting protein 3<br />
 
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**[[4uj3]], [[4uj4]] – hRab-11A (mutant) + Rab11 family-interacting protein 3 + Rab-3A interacting protein 3<br />
 
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**[[5jcz]] – hRab-11A + unconventional myosin-Va<br />
 
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**[[4lwz]], [[4lx0]] – hRab-11A + unconventional myosin-Vb<br />
 
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**[[4fmd]] – hRab-11A + EspG + GDP<br />
 
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**[[6djl]] – hRab-11A (mutant) + SH3 domain-binding protein 5<br />
 
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**[[5fbl]], [[5fbq]], [[5fbr]], [[5fbv]], [[5fbw]] – hRab-11A + PI4KB + inhibitor<br />
 
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**[[5c46]] – hRab-11A (mutant) + PI4KB + GDPγS<br />
 
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**[[5c4g]], [[5euq]], [[4d0l]] – hRab-11A (mutant) + PI4KB + GDPγS + inhibitor<br />
 
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*Rab-11B
 
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**[[2f9l]] – hRab-11B + GDP <br />
 
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**[[2f9m]] – hRab-11B + GNP <br />
 
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*Rab-12
 
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**[[2il1]] – hRab-12 + GDP <br />
 
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*Rab-14
 
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**[[4d0g]] – hRab-14 (mutant) + Rab11 family-interacting protein 1 <br />
 
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**[[4drz]], [[1z0f]] – hRab-14 + GDP <br />
 
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*Rab-18
 
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**[[1x3s]] – hRab-18 + GNP <br />
 
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*Rab-22
 
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**[[1yvd]] – mRab-22 + GNP <br />
 
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**[[1z0j]] – mRab-22 (mutant) + rabenosyn-5 + GTP <br />
 
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*Rab-23
 
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**[[1z22]], [[1z2a]] – mRab-23 + GDP<br />
 
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*Rab-25
 
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**[[2oil]] – hRab-25 + GDP <br />
 
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**[[3tso]] – hRab-25 + Rab11 family-interacting protein 2 <br />
 
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*Rab-26
 
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**[[2g6b]] – hRab-26 + GNP <br />
 
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*Rab-27
 
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**[[2f7s]] – hRab-27 + GDP <br />
 
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**[[2iey]], [[2iez]], [[2if0]] – mRab-27 + GDP <br />
 
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**[[2zet]] – mRab-27 + melanophilin + GDP <br />
 
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*Rab-28
 
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**[[2hxs]] – hRab-28 + G3D <br />
 
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**[[3e5h]] – hRab-28 + GND <br />
 
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*Rab-30
 
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**[[2ew1]] – hRab-30 + GNP <br />
 
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*Rab-31
 
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**[[2fg5]] – hRab-31 + GNP <br />
 
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*Rab-32
 
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**[[6ff8]] – hRab-32 + GTP <br />
 
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**[[5oed]], [[5oec]] – hRab-32 + GtgE + GDP <br />
 
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*Rab-33
 
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**[[1z06]] – mRab-33 + Gyp1 + GDP <br />
 
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**[[2g77]] – mRab-33 + GNP <br />
 
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**[[6zay]] – mRab-33 + Atg16L + GDP <br />
 
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**[[6y09]], [[6sur]] – mRab-33 + Atg16L + GTP <br />
 
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*Rab-35
 
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**[[6if2]] – hRab-35 + GTP <br />
 
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**[[6if3]] – hRab-35 + ACAP2 + GTP <br />
 
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**[[6ekk]] – hRab-35 + DENDD 1A + GDP <br />
 
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**[[3tw8]] – hRab-35 + DENDD 1B <br />
 
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*Rab-38
 
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**[[6s5h]], [[6hdu]] – hRab-38 + GTP <br />
 
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*Rab-39B
 
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**[[6s5f]] – hRab-39B + GMPPNP <br />
 
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*Rab-43
 
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**[[2hup]] – hRab-43 + GDP <br />
 
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}}
 
== References ==
== References ==

Revision as of 08:22, 18 October 2020

Human Rab-11A complex with GDP, phosphate and Mg+2 ion (green) (PDB code 1oix)

Drag the structure with the mouse to rotate

References

  1. Bhuin T, Roy JK. Rab11 in disease progression. Int J Mol Cell Med. 2015 Winter;4(1):1-8. PMID:25815277
  2. Pasqualato S, Senic-Matuglia F, Renault L, Goud B, Salamero J, Cherfils J. The structural GDP/GTP cycle of Rab11 reveals a novel interface involved in the dynamics of recycling endosomes. J Biol Chem. 2004 Mar 19;279(12):11480-8. Epub 2003 Dec 29. PMID:14699104 doi:10.1074/jbc.M310558200

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