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7k3g
From Proteopedia
(Difference between revisions)
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==SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by Solid-State NMR== | ==SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by Solid-State NMR== | ||
| - | <StructureSection load='7k3g' size='340' side='right'caption='[[7k3g]]' scene=''> | + | <StructureSection load='7k3g' size='340' side='right'caption='[[7k3g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[7k3g]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/2019-ncov 2019-ncov]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K3G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7K3G FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3g OCA], [http://pdbe.org/7k3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3g RCSB], [http://www.ebi.ac.uk/pdbsum/7k3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3g ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E, 4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2697049 2019-nCoV])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3g OCA], [http://pdbe.org/7k3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3g RCSB], [http://www.ebi.ac.uk/pdbsum/7k3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VEMP_SARS2 VEMP_SARS2]] Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis.[HAMAP-Rule:MF_04204] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: 2019-ncov]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Dregni | + | [[Category: Dregni, A J]] |
| - | [[Category: Hong M]] | + | [[Category: Hong, M]] |
| - | [[Category: Mandala | + | [[Category: Mandala, V S]] |
| - | [[Category: McKay | + | [[Category: McKay, M J]] |
| - | [[Category: Shcherbakov | + | [[Category: Shcherbakov, A S]] |
| + | [[Category: Pentameric ion channel]] | ||
| + | [[Category: Transmembrane domain]] | ||
| + | [[Category: Viral protein]] | ||
| + | [[Category: Viroporin]] | ||
Revision as of 08:44, 21 October 2020
SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by Solid-State NMR
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