This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7k3g
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by Solid-State NMR== | ==SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by Solid-State NMR== | ||
| - | <StructureSection load='7k3g' size='340' side='right'caption='[[7k3g]]' scene=''> | + | <StructureSection load='7k3g' size='340' side='right'caption='[[7k3g]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full | + | <table><tr><td colspan='2'>[[7k3g]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/2019-ncov 2019-ncov]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K3G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7K3G FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3g OCA], [http://pdbe.org/7k3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3g RCSB], [http://www.ebi.ac.uk/pdbsum/7k3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3g ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E, 4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2697049 2019-nCoV])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k3g OCA], [http://pdbe.org/7k3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k3g RCSB], [http://www.ebi.ac.uk/pdbsum/7k3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k3g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VEMP_SARS2 VEMP_SARS2]] Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis.[HAMAP-Rule:MF_04204] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: 2019-ncov]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Dregni | + | [[Category: Dregni, A J]] |
| - | [[Category: Hong M]] | + | [[Category: Hong, M]] |
| - | [[Category: Mandala | + | [[Category: Mandala, V S]] |
| - | [[Category: McKay | + | [[Category: McKay, M J]] |
| - | [[Category: Shcherbakov | + | [[Category: Shcherbakov, A S]] |
| + | [[Category: Pentameric ion channel]] | ||
| + | [[Category: Transmembrane domain]] | ||
| + | [[Category: Viral protein]] | ||
| + | [[Category: Viroporin]] | ||
Revision as of 08:44, 21 October 2020
SARS-CoV-2 Envelope Protein Transmembrane Domain: Pentameric Structure Determined by Solid-State NMR
| |||||||||||
