SAGA-associated factor

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**[[4w4u]], [[6aqr]] – ySGF11 + SUS1+ SGF73 + ubiquitin carboxyl terminal hydrolase<br />
**[[4w4u]], [[6aqr]] – ySGF11 + SUS1+ SGF73 + ubiquitin carboxyl terminal hydrolase<br />
**[[4zux]] – yUBP8 + SUS1 + SGF11 +SGF73 + ubiquitin + histone H3.2, H4, H2A, H2B + DNA<br />
**[[4zux]] – yUBP8 + SUS1 + SGF11 +SGF73 + ubiquitin + histone H3.2, H4, H2A, H2B + DNA<br />
 +
**[[6tbm]] – KpSGF + TBP + SPT20 + SPT8 + transcription coactivator HFI1 + TFIID + polyubiquitin + SUS1 + transcription-associated protein – ''Komagataela phaffii'' - Cryo EM<br />
*SGF29
*SGF29
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*SGF73
*SGF73
 +
**[[6t9i]], [[6t9k]], [[6t9l]] – ySGF in transcription coactivator SAGA – Cryo EM<br />
**[[2lo3]] – ySGF zinc finger domain – NMR<br />
**[[2lo3]] – ySGF zinc finger domain – NMR<br />
 +
**[[6tb4]] – KpSGF + TBP + SPT20 + transcription coactivator HFI1 + TFIID + ADA3 + transcription-associated protein - Cryo EM<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category: Topic Page]]
[[Category: Topic Page]]

Revision as of 09:37, 27 October 2020

Structure of SGF11 (pink) in the SAGA complex with Sus1 (green) , SGF73 (magenta), ubiquitin (yellow), UB8P (grey), glycerol and Zn+2 ions (grey) (PDB entry 3mhs)

Drag the structure with the mouse to rotate

3D structures of SAGA-associated factor

Updated on 27-October-2020

References

  1. Mischerikow N, Spedale G, Altelaar AF, Timmers HT, Pijnappel WW, Heck AJ. In-depth profiling of post-translational modifications on the related transcription factor complexes TFIID and SAGA. J Proteome Res. 2009 Nov;8(11):5020-30. doi: 10.1021/pr900449e. PMID:19731963 doi:http://dx.doi.org/10.1021/pr900449e
  2. Schram AW, Baas R, Jansen PW, Riss A, Tora L, Vermeulen M, Timmers HT. A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation. PLoS One. 2013 Jul 23;8(7):e70035. doi: 10.1371/journal.pone.0070035. Print 2013. PMID:23894581 doi:http://dx.doi.org/10.1371/journal.pone.0070035
  3. Deng X, Zhou H, Zhang G, Wang W, Mao L, Zhou X, Yu Y, Lu H. Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast. Sci Rep. 2015 Oct 7;5:14707. doi: 10.1038/srep14707. PMID:26443059 doi:http://dx.doi.org/10.1038/srep14707

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Michal Harel, Joel L. Sussman

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