1cwj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1cwj.gif|left|200px]]
[[Image:1cwj.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1cwj |SIZE=350|CAPTION= <scene name='initialview01'>1cwj</scene>, resolution 1.8&Aring;
+
The line below this paragraph, containing "STRUCTURE_1cwj", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=BIN:Cyclosporin+Binding+Site'>BIN</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MNV:N-METHYL-C-AMINO+VALINE'>MNV</scene>, <scene name='pdbligand=MSA:(2-S-METHYL)+SARCOSINE'>MSA</scene>, <scene name='pdbligand=TBM:4-METHYL-4-[(E)-2-BUTENYL]-4,N-DIMETHYL-THREONINE'>TBM</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE= CYCLOPHILIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1cwj| PDB=1cwj | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cwj OCA], [http://www.ebi.ac.uk/pdbsum/1cwj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1cwj RCSB]</span>
+
-
}}
+
'''HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN'''
'''HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN'''
Line 30: Line 27:
[[Category: Taylor, P.]]
[[Category: Taylor, P.]]
[[Category: Walkinshaw, M D.]]
[[Category: Walkinshaw, M D.]]
-
[[Category: complex (isomerase/immunosuppressant)]]
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 13:11:21 2008''
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:29:55 2008''
+

Revision as of 10:11, 2 May 2008

Image:1cwj.gif

Template:STRUCTURE 1cwj

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN


Overview

Eight new X-ray structures of different cyclophilin A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide a useful structural database for the analysis of protein-ligand interactions. The effect of small chemical differences on protein-ligand hydrogen-bonding, van der Waals interactions and water structure is presented.

About this Structure

1CWJ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A., Kallen J, Mikol V, Taylor P, Walkinshaw MD, J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:9769216 Page seeded by OCA on Fri May 2 13:11:21 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1cwj"
Personal tools