RNA polymerase 3D structures

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Line 34: Line 34:
**[[1eik]] - MtRNAP subunit RPB5 – NMR<br />
**[[1eik]] - MtRNAP subunit RPB5 – NMR<br />
**[[4qiw]] – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p – ''Thermococcus kodakarensis''<br />
**[[4qiw]] – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p – ''Thermococcus kodakarensis''<br />
 +
**[[6kf3]] – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p – Cryo EM<br />
**[[4qjf]] - TkRNAP subunits e’+f<br />
**[[4qjf]] - TkRNAP subunits e’+f<br />
**[[4qjv]] - TkRNAP subunits d+l<br />
**[[4qjv]] - TkRNAP subunits d+l<br />
**[[6eyd]], [[6f6w]] – MsRNAP subunits α,β,β',ω - ''Mycobacterium smegmatis'' – Cryo EM<br />
**[[6eyd]], [[6f6w]] – MsRNAP subunits α,β,β',ω - ''Mycobacterium smegmatis'' – Cryo EM<br />
 +
**[[6vr4]] – RNAP – Cellulophaga phage phi<br />
 +
**[[7ccg]] - RNAP subunit δ - ''Streptomyces albulus''<br />
*Prokaryotic DNA-dependent RNAP complex with DNA/RNA
*Prokaryotic DNA-dependent RNAP complex with DNA/RNA
Line 43: Line 46:
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br />
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br />
**[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] - TtRNAP subunits α,β,β',ω + DNA +RNA<br />
**[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] - TtRNAP subunits α,β,β',ω + DNA +RNA<br />
 +
**[[6m6c]] - TtRNAP subunits α,β,β',ω + RNA + DNA – Cryo EM<br />
**[[5x22]] - TtRNAP subunits α,β,β',ω + DNA + RNA + CMPCPP<br />
**[[5x22]] - TtRNAP subunits α,β,β',ω + DNA + RNA + CMPCPP<br />
**[[5x21]] - TtRNAP subunits α,β,β',ω + DNA + RNA + antibiotic<br />
**[[5x21]] - TtRNAP subunits α,β,β',ω + DNA + RNA + antibiotic<br />
Line 75: Line 79:
**[[6byu]] - EcRNAP subunits α,β,β’,ω + σ factor + PPAPP<br />
**[[6byu]] - EcRNAP subunits α,β,β’,ω + σ factor + PPAPP<br />
**[[5w1s]] - EcRNAP subunits α,β,β’,ω + σ factor + TRAR<br />
**[[5w1s]] - EcRNAP subunits α,β,β’,ω + σ factor + TRAR<br />
 +
**[[6p1k]] - EcRNAP subunits α,β,β’,ω + RPOD – Cryo EM<br />
 +
**[[6vjs]] - EcRNAP subunits α,β,β’,ω + RPOD + inhibitor<br />
 +
**[[6r9b]], [[6r9g]] - EcRNAP subunits α,β,β’,ω + OCR – Cryo EM<br />
 +
**[[6n57]], [[6n58]] - EcRNAP subunits α,β,β’,ω + RPOD + TRAR – Cryo EM<br />
**[[6rin]], [[6ri7]] - EcRNAP subunits α,β,β’,ω + GREB + RNA + DNA – Cryo EM<br />
**[[6rin]], [[6ri7]] - EcRNAP subunits α,β,β’,ω + GREB + RNA + DNA – Cryo EM<br />
**[[5tbz]] - EcRNAP subunits α,β,β’ + NusG – Cryo EM<br />
**[[5tbz]] - EcRNAP subunits α,β,β’ + NusG – Cryo EM<br />
Line 87: Line 95:
**[[3lpe ]]- MjRNAP subunit ε’’ + transcription antitermination protein<br />
**[[3lpe ]]- MjRNAP subunit ε’’ + transcription antitermination protein<br />
**[[6eyd]] - MsRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br />
**[[6eyd]] - MsRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br />
 +
**[[6kf4]] – TkRNAP subunits a’+d+e’+f+h+k+l+n+p + transcription factor E – Cryo EM<br />
 +
**[[6zfb]] - BsRNAP subunits α,β,β’,δ + HelD – Cryo EM<br />
*''Prokaryotic DNA-dependent RNAP complex with σ factor + DNA/RNA''
*''Prokaryotic DNA-dependent RNAP complex with σ factor + DNA/RNA''
 +
**[[6lts]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br />
**[[4oin]], [[4oio]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA<br />
**[[4oin]], [[4oio]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA<br />
**[[4oip]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide<br />
**[[4oip]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide<br />
**[[4oiq]], [[4oir]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic<br />
**[[4oiq]], [[4oir]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic<br />
**[[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[5d4d]], [[5d4e]], [[5voi]], [[6p70]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br />
**[[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[5d4d]], [[5d4e]], [[5voi]], [[6p70]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br />
-
**[[4q5s]], [[5d4c]], [[5e17]], [[5e18]], [[5vo8]], [[6p71]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br />
+
**[[4q5s]], [[5d4c]], [[5e17]], [[5e18]], [[5vo8]], [[6p71]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]], [[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br />
**[[5i2d]] - TtRNAP subunits α,β,β’,ω + σ factor + transcriptional regulator + DNA + RNA<br />
**[[5i2d]] - TtRNAP subunits α,β,β’,ω + σ factor + transcriptional regulator + DNA + RNA<br />
**[[6cuu]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br />
**[[6cuu]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br />
Line 109: Line 120:
**[[5ms0]] - EcRNAP subunits α,β,β’,ω + σ factor + NusB + NusG + NusA + antitermination protein + RS10 + DNA – Cryo EM<br />
**[[5ms0]] - EcRNAP subunits α,β,β’,ω + σ factor + NusB + NusG + NusA + antitermination protein + RS10 + DNA – Cryo EM<br />
**[[5uha]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA <br />
**[[5uha]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA <br />
-
**[[5uh9]], [[5uh8]], [[6jcy]], [[6jcx]], [[6jbq]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA <br />
+
**[[5uh9]], [[5uh8]], [[6jcy]], [[6jcx]], [[6jbq]], [[6kon]], [[6koo]], [[6kop]], [[6koq]], [[6tye]], [[6tyf]], [[6tyg]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA <br />
**[[5uhg]], [[5uhc]], [[5uh6]], [[5uh5]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + antibiotic<br />
**[[5uhg]], [[5uhc]], [[5uh6]], [[5uh5]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + antibiotic<br />
**[[5uhd]], [[5uhb]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br />
**[[5uhd]], [[5uhb]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br />
Line 118: Line 129:
**[[3aoh]], [[3aoi]] - TtRNAP subunits α,β,β’,ω + DNA + RNA + GFH1<br />
**[[3aoh]], [[3aoi]] - TtRNAP subunits α,β,β’,ω + DNA + RNA + GFH1<br />
 +
**[[6wox]], [[6woy]] - TtRNAP subunits α,β,β’,ω in transcription complex<br />
 +
**[[6m6a]], [[6m6b]] - TtRNAP subunits α,β,β’,ω + transcription-repair-coupling factor + DNA – Cryo EM<br />
**[[3t72]] - EcRNAP subunit β + Pho box DNA + PhoB<br />
**[[3t72]] - EcRNAP subunit β + Pho box DNA + PhoB<br />
**[[1lb2]], [[3n4m]] - EcRNAP subunit α + DNA + CAP<br />
**[[1lb2]], [[3n4m]] - EcRNAP subunit α + DNA + CAP<br />
Line 131: Line 144:
**[[6jnx]] - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA – Cryo EM<br />
**[[6jnx]] - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA – Cryo EM<br />
**[[6p18]] - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA + RNA – Cryo EM<br />
**[[6p18]] - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA + RNA – Cryo EM<br />
 +
**[[6kj6]] - EcRNAP subunits α,β,β’,ω + RPOS + σ factor-binding protein CRL + DNA + RNA – Cryo EM<br />
 +
**[[6n4c]], [[6oul]], [[6wr6]], [[6wr8]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA – Cryo EM<br />
 +
**[[6ldi]] - EcRNAP subunits α,β,β’,ω + RPOD + CUER + DNA + RNA – Cryo EM<br />
 +
**[[6pb4]], [[6pb5]], [[6pb6]] - EcRNAP subunits α,β,β’,ω + RPOD + CRP + DNA + RNA – Cryo EM<br />
 +
**[[6psq]], [[6psr]], [[6pss]], [[6pst]], [[6psu]], [[6psv]], [[6psw]] - EcRNAP subunits α,β,β’,ω + RPOD + TRAR + DNA + RNA – Cryo EM<br />
 +
**[[6pmi]], [[6pmj]] - EcRNAP subunits α,β,β’,ω + FLIA + DNA + RNA – Cryo EM<br />
 +
**[[6rin]], [[6ri7]] - EcRNAP subunits α,β,β’,ω + GREB + RNA + DNA – Cryo EM<br />
 +
**[[6tqn]], [[6tqo]] - EcRNAP subunits α,β,β’,ω in anti-termination complex – Cryo EM<br />
 +
**[[7c17]] - EcRNAP subunits α,β,β’,ω in transcription complex – Cryo EM<br />
 +
**[[7c97]], [[7chw]] - EcRNAP subunits α,β,β’,ω in promoter-open complex – Cryo EM<br />
**[[6j9f]] - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA – Xanthomonas oryzae - Cryo EM<br />
**[[6j9f]] - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA – Xanthomonas oryzae - Cryo EM<br />
**[[6j9e]] - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA + NusA - Cryo EM<br />
**[[6j9e]] - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA + NusA - Cryo EM<br />
 +
**[[6kf9]] – TkRNAP subunits a’’+d+e’+f+h+k+l+n+p + transcription factor E + DNA – Cryo EM<br />
 +
**[[6dve]], [[6dvd]], [[6dvc]], [[6dvb]], [[6dv9]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA<br />
 +
**[[5zx2]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br />
 +
*''Prokaryotic DNA-dependent RNAP complex with small molecule''
*''Prokaryotic DNA-dependent RNAP complex with small molecule''
Line 153: Line 180:
**[[5n61]], [[6h68]], [[6h67]] – yRNAP I + RRN + DNA + RNA – Cryo EM<br />
**[[5n61]], [[6h68]], [[6h67]] – yRNAP I + RRN + DNA + RNA – Cryo EM<br />
**[[5w66]], [[5w65]], [[5w64]], [[5w5y]] – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM<br />
**[[5w66]], [[5w65]], [[5w64]], [[5w5y]] – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM<br />
 +
**[[6tps]] – yRNAP I in pre-initiation complex – Cryo EM<br />
*Eukaryotic DNA-dependent RNAP II
*Eukaryotic DNA-dependent RNAP II
Line 197: Line 225:
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br />
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br />
**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br />
**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br />
 +
**[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]] - yRNAP II in elongation complex<br />
**[[6gml]] – pRNAP II + RNA + DNA + DSIF + NELF – pig – Cryo EM<br />
**[[6gml]] – pRNAP II + RNA + DNA + DSIF + NELF – pig – Cryo EM<br />
-
**[[6gmh]] – pRNAP II + RNA + DNA + DSIF + PAF + SPT6 – Cryo EM<br />
+
**[[6gmh]], [[6ted]] – pRNAP II + RNA + DNA + DSIF + PAF + SPT6 – Cryo EM<br />
**[[6exv]] – pRNAP II + RNA + DNA + amatoxin – Cryo EM<br />
**[[6exv]] – pRNAP II + RNA + DNA + amatoxin – Cryo EM<br />
Line 221: Line 250:
**[[5xog]] - yRNAP III + DNA + RNA + SPT5 + KOW5 + ELF1 – Cryo EM<br />
**[[5xog]] - yRNAP III + DNA + RNA + SPT5 + KOW5 + ELF1 – Cryo EM<br />
**[[6eu0]] - yRNAP III + DNA + TFIIIB + TATA-box-binding protein – Cryo EM<br />
**[[6eu0]] - yRNAP III + DNA + TFIIIB + TATA-box-binding protein – Cryo EM<br />
 +
**[[6tut]] - yRNAP III complex + MAF1 – Cryo EM<br />
**[[3ayh]] - fyRNAP III subunit Rpc8+Rpc9<br />
**[[3ayh]] - fyRNAP III subunit Rpc8+Rpc9<br />
Line 269: Line 299:
**[[4bpx]] - hDNAP small (mutant) + DNA polymerase α catalytic subunit<br />
**[[4bpx]] - hDNAP small (mutant) + DNA polymerase α catalytic subunit<br />
**[[5exr]] - hDNAP small + large subunits + DNA polymerase α catalytic subunit<br />
**[[5exr]] - hDNAP small + large subunits + DNA polymerase α catalytic subunit<br />
- 
*''Bacterial DNA primase''
*''Bacterial DNA primase''
Line 358: Line 387:
**[[4gzk]], [[4ieg]] – RNAP – cystovirus 12<br />
**[[4gzk]], [[4ieg]] – RNAP – cystovirus 12<br />
**[[4i1t]] – RNAP L – Pichinde virus <br />
**[[4i1t]] – RNAP L – Pichinde virus <br />
-
**[[5chs]] – RNAP L N-terminal – Vescicular stomatitis Indiana virus <br />
+
**[[5chs]] – VsivRNAP L N-terminal – Vescicular stomatitis Indiana virus <br />
**[[4xha]], [[4xhi]] – TavRNAP – Thosea asigna virus <br />
**[[4xha]], [[4xhi]] – TavRNAP – Thosea asigna virus <br />
 +
**[[6l42]] – RNAP L – Phlebovirus – Cryo EM<br />
 +
**[[6l4r]] – RNAP – Enterovirus <br />
 +
**[[6ntv]] – SftvRNAP – Severe fever with thrombocytopenia virus – Cryo EM<br />
 +
**[[6ntv]] – SftvRNAP endonuclease domain 1-226<br />
 +
**[[6lkx]] – RNAP – Porcine respiratory virus <br />
 +
**[[6kld]] – RNAP L – Machupo virus – Cryo EM<br />
 +
**[[6klc]] – LvRNAP L – Lassa virus – Cryo EM<br />
**[[4miw]], [[5izh]], [[5j1n]], [[5j1p]] – RNAP L N terminal – Lassa virus <br />
**[[4miw]], [[5izh]], [[5j1n]], [[5j1p]] – RNAP L N terminal – Lassa virus <br />
**[[4mtp]] – RNAP RDRP module – Encephalitis virus <br />
**[[4mtp]] – RNAP RDRP module – Encephalitis virus <br />
Line 370: Line 406:
**[[5ltf]] – LcmvRNAP L – Lymphocytic choriomeningitis mammarenavirus<br />
**[[5ltf]] – LcmvRNAP L – Lymphocytic choriomeningitis mammarenavirus<br />
**[[5lts]] - LcmvRNAP (mutant)<br />
**[[5lts]] - LcmvRNAP (mutant)<br />
-
**[[5u0c]] - ZvRNAP NS5 – Zika virus<br />
+
**[[5u0c]], [[6ld1]] - ZvRNAP NS5 polymerase domain 2781-3419 – Zika virus<br />
**[[6qw5]], [[6qw0]], [[6qvv]] - RNAP – Toscana virus<br />
**[[6qw5]], [[6qw0]], [[6qvv]] - RNAP – Toscana virus<br />
**[[6dx5]] - RNAP OTU domain – Farallon virus<br />
**[[6dx5]] - RNAP OTU domain – Farallon virus<br />
Line 398: Line 434:
**[[6kwq]] – EvRNAP + RNA<br />
**[[6kwq]] – EvRNAP + RNA<br />
**[[6kwr]] – EvRNAP + RNA + CMP + CTP<br />
**[[6kwr]] – EvRNAP + RNA + CMP + CTP<br />
 +
**[[6kle]], [[6klh]] – MvRNAP L + RNA – Cryo EM<br />
 +
**[[6z6g]], [[6z8k]] – RNAP L + RNA – La crosse orthobunyavirus - Cryo EM<br />
*''RNA-dependent RNAP complex with protein''
*''RNA-dependent RNAP complex with protein''
Line 404: Line 442:
**[[3phx]], [[3pse]] – HfRNAP + ISG15<br />
**[[3phx]], [[3pse]] – HfRNAP + ISG15<br />
**[[6u5o]] – HmpvRNAP L + phosphoprotein – Cryo EM<br />
**[[6u5o]] – HmpvRNAP L + phosphoprotein – Cryo EM<br />
-
**[[6pzk]] – RNAP L + phosphoprotein – Human respiratory syncytial virus - Cryo EM<br />
+
**[[6pzk]], [[6uen]] – RNAP L + phosphoprotein – Human respiratory syncytial virus - Cryo EM<br />
 +
**[[6v85]], [[6v86]] – RNAP L + phosphoprotein – Parainfluenza virus <br />
**[[6po2]], [[6pns]] – RNAP + VP3 – Bluetongue virus - Cryo EM<br />
**[[6po2]], [[6pns]] – RNAP + VP3 – Bluetongue virus - Cryo EM<br />
**[[2d7s]], [[2f8e]] – FmRNAP + VPG <br />
**[[2d7s]], [[2f8e]] – FmRNAP + VPG <br />
Line 411: Line 450:
**[[4f5x]] – SrRNAP + Vp2 + Vp6<br />
**[[4f5x]] – SrRNAP + Vp2 + Vp6<br />
**[[3zed]] – IpnvRNAP + capsid protein Vp3<br />
**[[3zed]] – IpnvRNAP + capsid protein Vp3<br />
 +
**[[6u1x]] – VsivRNAP + phosphoprotein <br />
**[[4hxd]] – RNAP L + polyubiquitin-C – Dugbe virus<br />
**[[4hxd]] – RNAP L + polyubiquitin-C – Dugbe virus<br />
**[[4r71]] – RNAP b chain + EF-TS EF-TU + RPS1 – Enterobacteria phage qbeta<br />
**[[4r71]] – RNAP b chain + EF-TS EF-TU + RPS1 – Enterobacteria phage qbeta<br />
Line 418: Line 458:
**[[6ogy]] – RvARNAP + Vp2 + RNA – Cryo EM<br />
**[[6ogy]] – RvARNAP + Vp2 + RNA – Cryo EM<br />
**[[6k32]] – RvARNAP + Vp1 + Vp4 + RNA – Cypovirus 1 - Cryo EM<br />
**[[6k32]] – RvARNAP + Vp1 + Vp4 + RNA – Cypovirus 1 - Cryo EM<br />
 +
**[[6oar]], [[6oat]] – RNAP OUT domain + ISG17 – Kupe virus <br />
 +
**[[6xqb]], [[7bzf]], [[7c2k]] – RNAP + non-structural proteins + RNA – SARS-COV-2 - Cryo EM<br />
*''RNA-dependent RNAP complex with small molecule''
*''RNA-dependent RNAP complex with small molecule''
Line 435: Line 477:
**[[1hi1]] – P6RNAP + NTP<br />
**[[1hi1]] – P6RNAP + NTP<br />
**[[5cx6]], [[5cyr]] - TavRNAP + nucleotide<br />
**[[5cx6]], [[5cyr]] - TavRNAP + nucleotide<br />
-
**[[5hmw]], [[5f3t]], [[5hmx]], [[5hmy]], [[5hn0]], [[5hmz]], [[5iq6]], [[5k5m]] - DevRNAP Ns5 + inhibitor<br />
+
**[[5hmw]], [[5f3t]], [[5hmx]], [[5hmy]], [[5hn0]], [[5hmz]], [[5iq6]], [[5k5m]], [[6xd0]], [[6xd1]] - DevRNAP Ns5 + inhibitor<br />
**[[5ehg]] - DevRNAP NS5 + SAM + inhibitor<br />
**[[5ehg]] - DevRNAP NS5 + SAM + inhibitor<br />
**[[5goz]], [[5gp1]] - ZvRNAP NS5 + SAH + GTP <br />
**[[5goz]], [[5gp1]] - ZvRNAP NS5 + SAH + GTP <br />
 +
**[[6ld2]], [[6ld3]], [[6ld4]], [[6ld5]] - ZvRNAP NS5 polymerase domain + inhibitor <br />
**[[5ltn]], [[5t2t]] - LcmvRNAP + inhibitor<br />
**[[5ltn]], [[5t2t]] - LcmvRNAP + inhibitor<br />
**[[6mvo]] – RNAP (mutant) + inhibitor – Hepacivirus C<br />
**[[6mvo]] – RNAP (mutant) + inhibitor – Hepacivirus C<br />
 +
**[[6xya]] – SftvRNAP cap-binding domain 1695-1810 + GTP <br />
 +
*Influenza virus polymerase acidic protein (or PA or subunit P2) N terminal 1-198
*Influenza virus polymerase acidic protein (or PA or subunit P2) N terminal 1-198
Line 448: Line 493:
**[[4iuj]] - IvRNAP PA residues 254-713<br />
**[[4iuj]] - IvRNAP PA residues 254-713<br />
**[[3hw3]], [[3hw4]], [[3hw5]] - IvRNAP PA residues 1-256 (mutant) + Mn + nucleotide <br />
**[[3hw3]], [[3hw4]], [[3hw5]] - IvRNAP PA residues 1-256 (mutant) + Mn + nucleotide <br />
-
**[[4w9s]], [[5fdd]], [[5fdg]], [[5i13]], [[5ieq]], [[5if2]], [[5if5]], [[5if7]], [[5if8]], [[5ifb]], [[5ifc]], [[5ifd]], [[5wa6]], [[5wa7]], [[5wb3]], [[5wap]], [[5w9g]], [[5w92]], [[5w44]], [[5v0u]], [[6nem]], [[6nel]], [[6e6x]], [[6e6w]], [[6e6v]], [[6dcz]], [[6dcy]], [[5ega]], [[5cl0]], [[5cgv]], [[5ccy]], [[4mk5]], [[4mk2]], [[4mk1]], [[4awm]], [[4awk]], [[4awh]], [[4awg]], [[4awf]], [[4e5f]], [[4e5g]], [[4e5h]], [[4e5i]], [[4e5j]], [[4e5l]], [[4yyl]], [[4zhz]], [[4zi0]], [[6fs7]], [[6fs6]], [[6fs8]], [[4avl]], [[4avg]] – IvRNAP PA N terminal + inhibitor<br />
+
**[[4w9s]], [[5fdd]], [[5fdg]], [[5i13]], [[5ieq]], [[5if2]], [[5if5]], [[5if7]], [[5if8]], [[5ifb]], [[5ifc]], [[5ifd]], [[5wa6]], [[5wa7]], [[5wb3]], [[5wap]], [[5w9g]], [[5w92]], [[5w44]], [[5v0u]], [[6nem]], [[6nel]], [[6e6x]], [[6e6w]], [[6e6v]], [[6dcz]], [[6dcy]], [[5ega]], [[5cl0]], [[5cgv]], [[5ccy]], [[4mk5]], [[4mk2]], [[4mk1]], [[4awm]], [[4awk]], [[4awh]], [[4awg]], [[4awf]], [[4e5f]], [[4e5g]], [[4e5h]], [[4e5i]], [[4e5j]], [[4e5l]], [[4yyl]], [[4zhz]], [[4zi0]], [[6fs7]], [[6fs6]], [[6fs8]], [[4avl]], [[4avg]], [[6yem]] – IvRNAP PA N terminal + inhibitor<br />
**[[5wg9]], [[5wfz]], [[5wfw]], [[5wfm]], [[5wf3]], [[5wei]], [[5wef]], [[5web]], [[5we9]], [[5we7]], [[5wdw]], [[5wdn]], [[5wdc]], [[5wct]], [[5wcs]], [[5w73]], [[5w7u]], [[5w3i]], [[5vrj]], [[5vqn]], [[5vpx]], [[5vpt]], [[5vp8]], [[6e4c]], [[6e3p]], [[6e3o]], [[6e3n]], [[6e3m]], [[6e0q]], [[6dzq]], [[5deb]], [[5dbs]], [[5d9j]], [[5d8u]], [[5d4g]], [[5d42]], [[6fs9]] – IvRNAP PA N terminal (mutant) + inhibitor<br />
**[[5wg9]], [[5wfz]], [[5wfw]], [[5wfm]], [[5wf3]], [[5wei]], [[5wef]], [[5web]], [[5we9]], [[5we7]], [[5wdw]], [[5wdn]], [[5wdc]], [[5wct]], [[5wcs]], [[5w73]], [[5w7u]], [[5w3i]], [[5vrj]], [[5vqn]], [[5vpx]], [[5vpt]], [[5vp8]], [[6e4c]], [[6e3p]], [[6e3o]], [[6e3n]], [[6e3m]], [[6e0q]], [[6dzq]], [[5deb]], [[5dbs]], [[5d9j]], [[5d8u]], [[5d4g]], [[5d42]], [[6fs9]] – IvRNAP PA N terminal (mutant) + inhibitor<br />
Line 477: Line 522:
**[[5fml]] - IvRNAP PA N terminal + PB2 NLS peptide<br />
**[[5fml]] - IvRNAP PA N terminal + PB2 NLS peptide<br />
 +
**[[6szu]], [[6szv]], [[6t0n]], [[6t0r]], [[6t0s]], [[6t0u]], [[6t0v]], [[6t0w]], [[6t2c]], [[6tw1]] - IvRNAP PA + PB2 + RNA-directed RNAP + RNA<br />
*Influenza virus RNAP PB1+PB2
*Influenza virus RNAP PB1+PB2
Line 496: Line 542:
**[[6fhh]] - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + POL II peptide<br />
**[[6fhh]] - IvRNAP PB1 + IvRNAP PA + IvRNAP PB2 + POL II peptide<br />
-
*Poly(A) RNA polymerase
+
*Poly(A) RNA polymerase see [[Poly(A) RNA polymerase]]
-
 
+
-
**[[3pq1]] – hRNAP (mutant)<br />
+
-
**[[4lt6]] – hRNAP γ <br />
+
-
**[[4nkt]] – SpRNAP (mutant) + UMPNPP <br />
+
-
**[[4nku]] – SpRNAP (mutant) + RNA <br />
+
-
**[[3nyb]] – yRNAP + AIR2<br />
+
-
**[[4e7x]], [[4e80]], [[4e8f]], [[4ep7]], [[4fh3]] – fyRNAP Cid1 <br />
+
-
**[[4fh5]], [[4fhp]], [[4fhv]], [[4fhw]], [[4fhy]] – fyRNAP Cid1 + nucleotide<br />
+
-
**[[4ud4]], [[4ud5]] - fyRNAP Cid1 (mutant)<br />
+
-
**[[4fhx]] – fyRNAP Cid1 (mutant) + ATP<br />
+
-
**[[4zrl]] – CeRNAP gld-2 + germline development defective 3 – ''Caenorhabidis elegans'' <br />
+
-
**[[5jnb]] – CeRNAP gld-2 (mutant) + RNP-8 <br />
+
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:08, 1 November 2020

3D Structures of RNA polymerase

Updated on 01-November-2020




Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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