Signal recognition particle protein
From Proteopedia
(Difference between revisions)
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*Signal recognition particle | *Signal recognition particle | ||
| + | **[[1qb2]] – hSRP54 - human<br /> | ||
| + | **[[4p3f]] – hSRP68 (mutant)<br /> | ||
| + | **[[5m72]], [[5wrv]] – hSRP68 + SRP72<br /> | ||
| + | **[[5wrw]] – hSRP72<br /> | ||
**[[1914]] – mSRP9/SRP14 – mouse<br /> | **[[1914]] – mSRP9/SRP14 – mouse<br /> | ||
**[[1wgw]] – mSRP54 N terminal – NMR<br /> | **[[1wgw]] – mSRP54 N terminal – NMR<br /> | ||
| - | **[[1ls1]], [[2j45]], [[2j46]], [[1ffh]], [[1ng1]], [[3ng1]] - TaSRP54-like NG domain – ''Thermus aquaticus''<br /> | ||
| - | **[[2ng1]] - TaSRP54-like NG domain (mutant)<br /> | ||
| - | **[[2ffh]] - TaSRP54-like residues 1-425 (mutant)<br /> | ||
| - | **[[1kvn]], [[1kvv]] – SRP19 (mutant) – ''Archaeoglobus fulgidus'' – NMR<BR /> | ||
| - | **[[1qb2]] – hSRP54 <br /> | ||
**[[2hug]] – AtSRP43 chromodomain 2 + SRP54 M domain – ''Arabidopsis thaliana'' – NMR<BR /> | **[[2hug]] – AtSRP43 chromodomain 2 + SRP54 M domain – ''Arabidopsis thaliana'' – NMR<BR /> | ||
**[[1x32]] - AtSRP43 chromodomain 1 – NMR<br /> | **[[1x32]] - AtSRP43 chromodomain 1 – NMR<br /> | ||
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**[[3deo]] - AtSRP43 residues 85-267<br /> | **[[3deo]] - AtSRP43 residues 85-267<br /> | ||
**[[3ui2]] - AtSRP43 residues 84-327 + AtSRP54 RRKR motif<br /> | **[[3ui2]] - AtSRP43 residues 84-327 + AtSRP54 RRKR motif<br /> | ||
| - | **[[3dlu]], [[3dlv]], [[3dm5]] – SRP19 – ''Pyrococcus furiosus''<br /> | ||
**[[2w9j]] – SRP14 residues 1-91 – fission yeast<br /> | **[[2w9j]] – SRP14 residues 1-91 – fission yeast<br /> | ||
| + | **[[1ls1]], [[2j45]], [[2j46]], [[1ffh]], [[1ng1]], [[3ng1]] - TaSRP54-like NG domain – ''Thermus aquaticus''<br /> | ||
| + | **[[2ng1]] - TaSRP54-like NG domain (mutant)<br /> | ||
| + | **[[2ffh]] - TaSRP54-like residues 1-425 (mutant)<br /> | ||
| + | **[[1kvn]], [[1kvv]] – SRP19 (mutant) – ''Archaeoglobus fulgidus'' – NMR<BR /> | ||
| + | **[[3dlu]], [[3dlv]], [[3dm5]] – SRP19 – ''Pyrococcus furiosus''<br /> | ||
**[[1j8m]] – AaSPR GTPase domain – ''Acicianus ambivalens''<br /> | **[[1j8m]] – AaSPR GTPase domain – ''Acicianus ambivalens''<br /> | ||
**[[1j8y]] – AaSPR GTPase domain (mutant)<br /> | **[[1j8y]] – AaSPR GTPase domain (mutant)<br /> | ||
**[[1qzx]] – SsSRP54 – ''Sulfolobus solfataricus''<br /> | **[[1qzx]] – SsSRP54 – ''Sulfolobus solfataricus''<br /> | ||
| - | **[[4p3f]] – hSRP68 (mutant) – human<br /> | ||
| - | **[[5m72]], [[5wrv]] – hSRP68 + SRP72<br /> | ||
| - | **[[5wrw]] – hSRP72<br /> | ||
*Signal recognition particle complexes with RNA | *Signal recognition particle complexes with RNA | ||
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**[[1jid]] – hSRP19 + RNA<br /> | **[[1jid]] – hSRP19 + RNA<br /> | ||
**[[3ktv]] - hSRP19 + RNA S domain<br /> | **[[3ktv]] - hSRP19 + RNA S domain<br /> | ||
| + | **[[1mfq]] – hSRP19 + hSRP54 M domain + 7S RNA S domain<br /> | ||
| + | **[[2j37]] - hSRP19 + SRP54 + ribosomal proteins L23, L31, L35 + RNA – Cryo EM<BR /> | ||
| + | **[[2go5]] – dSRP19 + SRP54 + hSRP receptor α subunit + mSRP receptor b subunit + ribosomal proteins L23, L31, L35 + RNA – dog<br /> | ||
| + | **[[4ue5]] – dSRP9 + SRP14 + SRP54 + SRP68 + RNA – Cryo EM<br /> | ||
**[[3ktw]] - SsSRP19 + RNA S domain <br /> | **[[3ktw]] - SsSRP19 + RNA S domain <br /> | ||
**[[1qzw]] – SsSRP + 7S RNA<br /> | **[[1qzw]] – SsSRP + 7S RNA<br /> | ||
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**[[1l9a]] - MjSRP19 (mutant) + RNA<br /> | **[[1l9a]] - MjSRP19 (mutant) + RNA<br /> | ||
**[[2v3c]], [[3ndb]], [[4xco]] - MjSRP19 + MjSRP54 + 7S RNA<br /> | **[[2v3c]], [[3ndb]], [[4xco]] - MjSRP19 + MjSRP54 + 7S RNA<br /> | ||
| - | **[[1mfq]] – hSRP19 + hSRP54 M domain + 7S RNA S domain<br /> | ||
**[[2iy3]] – TaSRP54-like + RNA - EM<BR /> | **[[2iy3]] – TaSRP54-like + RNA - EM<BR /> | ||
**[[1dul]], [[1hq1]], [[2pxp]] – EcSRP54-like C terminal + RNA – ''Escherichia coli''<br /> | **[[1dul]], [[1hq1]], [[2pxp]] – EcSRP54-like C terminal + RNA – ''Escherichia coli''<br /> | ||
**[[3lqx]] - EcSRP54-like + RNA + Co-hexamine<br /> | **[[3lqx]] - EcSRP54-like + RNA + Co-hexamine<br /> | ||
| - | **[[2xkv]] - EcSRP54-like NG+M domains + 4.5SRNA – EM<BR /> | + | **[[2xkv]] - EcSRP54-like NG+M domains + 4.5SRNA – Cryo EM<BR /> |
**[[2xxa]] - EcSRP54-like residues 1-433 (mutant) + cell division protein FtsY residues 196-497+ 4.5SRNA<br /> | **[[2xxa]] - EcSRP54-like residues 1-433 (mutant) + cell division protein FtsY residues 196-497+ 4.5SRNA<br /> | ||
**[[3zn8]] - EcSRP54 NG domain + cell division protein FtsY residues 201-495+ 4.5SRNA + dipeptidyl aminopeptidase B<br /> | **[[3zn8]] - EcSRP54 NG domain + cell division protein FtsY residues 201-495+ 4.5SRNA + dipeptidyl aminopeptidase B<br /> | ||
**[[2pxb]], [[2pxd]], [[2pxe]], [[2pxf]], [[2pxk]], [[2pxl]], [[2pxq]], [[2pxq]], [[2pxt]], [[2pxu]], [[2pxv]] - EcSRP54-like C terminal + 4.5SRNA domain IV (mutant)<br /> | **[[2pxb]], [[2pxd]], [[2pxe]], [[2pxf]], [[2pxk]], [[2pxl]], [[2pxq]], [[2pxq]], [[2pxt]], [[2pxu]], [[2pxv]] - EcSRP54-like C terminal + 4.5SRNA domain IV (mutant)<br /> | ||
| - | **[[2go5]] – dSRP19 + SRP54 + hSRP receptor α subunit + mSRP receptor b subunit + ribosomal proteins L23, L31, L35 + RNA – dog<br /> | ||
| - | **[[4ue5]] – dSRP9 + SRP14 + SRP54 + SRP68 + RNA – Cryo EM<br /> | ||
**[[2j28]] – EcSRP54-like + 70S ribosome – Cryo EM<BR /> | **[[2j28]] – EcSRP54-like + 70S ribosome – Cryo EM<BR /> | ||
| - | **[[2j37]] - SRP19 + SRP54 + ribosomal proteins L23, L31, L35 + RNA – wheat – Cryo EM<BR /> | ||
**[[4ue4]] – SRP M domain + FTSQ signal sequence + RNA - ''Bacillus subtilis''<br /> | **[[4ue4]] – SRP M domain + FTSQ signal sequence + RNA - ''Bacillus subtilis''<br /> | ||
*Other signal recognition particle complexes | *Other signal recognition particle complexes | ||
| + | **[[5l3q]] – hSRP54 + SRP receptor subunit α<br /> | ||
| + | **[[3dep]] - AtSRP43 residues 85-267 + polypeptide<br /> | ||
| + | **[[5e4w]] - AtSRP43 chromodomain 2-3 + thioredoxin + ALB3 tail<br /> | ||
| + | **[[5l3r]] - AtSRP54 + cell division protein FTSY<br /> | ||
**[[1jpj]], [[1jpn]], [[2c04]] – TaSRP54-like NG domain + GMPPNP<BR /> | **[[1jpj]], [[1jpn]], [[2c04]] – TaSRP54-like NG domain + GMPPNP<BR /> | ||
**[[1o87]], [[2c03]] - TaSRP54-like NG domain + GDP<br /> | **[[1o87]], [[2c03]] - TaSRP54-like NG domain + GDP<br /> | ||
**[[1okk]], [[1rj9]], [[2cnw]] - TaSRP54-like NG domain + cell division protein FTSY<br /> | **[[1okk]], [[1rj9]], [[2cnw]] - TaSRP54-like NG domain + cell division protein FTSY<br /> | ||
**[[2j7p]] - TaSRP54-like NG domain + cell division protein FTSY + GMPPNP<BR /> | **[[2j7p]] - TaSRP54-like NG domain + cell division protein FTSY + GMPPNP<BR /> | ||
| - | **[[3dep]] - AtSRP43 residues 85-267 + polypeptide<br /> | ||
| - | **[[5e4w]] - AtSRP43 chromodomain 2-3 + thioredoxin + ALB3 tail<br /> | ||
| - | **[[5l3r]] - AtSRP54 + cell division protein FTSY<br /> | ||
**[[5l3s]] - SsSRP54 + cell division protein FTSY<br /> | **[[5l3s]] - SsSRP54 + cell division protein FTSY<br /> | ||
**[[3kl4]] – SsSRP54 residues 2-432 + polypeptide<br /> | **[[3kl4]] – SsSRP54 residues 2-432 + polypeptide<br /> | ||
**[[5l3v]] - SsSRP54 + GDP<br /> | **[[5l3v]] - SsSRP54 + GDP<br /> | ||
**[[4c7o]] – EcSRP + FTSY + SRP RNA<br /> | **[[4c7o]] – EcSRP + FTSY + SRP RNA<br /> | ||
| - | + | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:35, 4 November 2020
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3D structures of signal recognition particle
Updated on 04-November-2020
References
- ↑ Halic M, Beckmann R. The signal recognition particle and its interactions during protein targeting. Curr Opin Struct Biol. 2005 Feb;15(1):116-25. PMID:15718142 doi:http://dx.doi.org/10.1016/j.sbi.2005.01.013
- ↑ Bovia F, Fornallaz M, Leffers H, Strub K. The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs. Mol Biol Cell. 1995 Apr;6(4):471-84. PMID:7542942
- ↑ Dean KA, von Ahsen O, Gorlich D, Fried HM. Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. J Cell Sci. 2001 Oct;114(Pt 19):3479-85. PMID:11682607
- ↑ Gowda K, Black SD, Moeller I, Sakakibara Y, Liu MC, Zwieb C. Protein SRP54 of human signal recognition particle: cloning, expression, and comparative analysis of functional sites. Gene. 1998 Jan 30;207(2):197-207. PMID:9511762
- ↑ Lutcke H, Prehn S, Ashford AJ, Remus M, Frank R, Dobberstein B. Assembly of the 68- and 72-kD proteins of signal recognition particle with 7S RNA. J Cell Biol. 1993 Jun;121(5):977-85. PMID:8388879
