1xl2
From Proteopedia
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(New page: 200px<br /> <applet load="1xl2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xl2, resolution 1.50Å" /> '''HIV-1 Protease in c...)
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Revision as of 12:29, 8 November 2007
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HIV-1 Protease in complex with pyrrolidinmethanamine
About this Structure
1XL2 is a Single protein structure of sequence from Human immunodeficiency virus 1 with CL, 189 and GOL as ligands. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
Reference
An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136
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