6rx7
From Proteopedia
(Difference between revisions)
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==Structure of the KIV type 2 (KIV-2) domain of lipoprotein (a)== | ==Structure of the KIV type 2 (KIV-2) domain of lipoprotein (a)== | ||
| - | <StructureSection load='6rx7' size='340' side='right'caption='[[6rx7]]' scene=''> | + | <StructureSection load='6rx7' size='340' side='right'caption='[[6rx7]], [[Resolution|resolution]] 1.63Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RX7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RX7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6rx7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RX7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6RX7 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rx7 OCA], [http://pdbe.org/6rx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rx7 RCSB], [http://www.ebi.ac.uk/pdbsum/6rx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rx7 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6rx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rx7 OCA], [http://pdbe.org/6rx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rx7 RCSB], [http://www.ebi.ac.uk/pdbsum/6rx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rx7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/APOA_HUMAN APOA_HUMAN]] Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.<ref>PMID:2531657</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Maggi M]] | + | [[Category: Maggi, M]] |
| - | [[Category: Santonastaso A]] | + | [[Category: Santonastaso, A]] |
| - | [[Category: Scotti C]] | + | [[Category: Scotti, C]] |
| + | [[Category: Kiv-2]] | ||
| + | [[Category: Kringle iv type 2]] | ||
| + | [[Category: Lipid transport]] | ||
Revision as of 08:08, 11 November 2020
Structure of the KIV type 2 (KIV-2) domain of lipoprotein (a)
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