6bgh

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==Solution NMR structure of Brd3 ET domain bound to Brg1 peptide==
==Solution NMR structure of Brd3 ET domain bound to Brg1 peptide==
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<StructureSection load='6bgh' size='340' side='right' caption='[[6bgh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='6bgh' size='340' side='right'caption='[[6bgh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6bgh]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6bgh]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6BGH FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgh OCA], [http://pdbe.org/6bgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgh RCSB], [http://www.ebi.ac.uk/pdbsum/6bgh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgh ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6bgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgh OCA], [http://pdbe.org/6bgh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgh RCSB], [http://www.ebi.ac.uk/pdbsum/6bgh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgh ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BRD3_HUMAN BRD3_HUMAN]] Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene.<ref>PMID:18406326</ref>
[[http://www.uniprot.org/uniprot/BRD3_HUMAN BRD3_HUMAN]] Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene.<ref>PMID:18406326</ref>
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==See Also==
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*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mackay, J P]]
[[Category: Mackay, J P]]
[[Category: Szyszka, T N]]
[[Category: Szyszka, T N]]

Revision as of 08:49, 11 November 2020

Solution NMR structure of Brd3 ET domain bound to Brg1 peptide

PDB ID 6bgh

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